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Principal Systems Engineer - Digital Lab & Automation Systems

Moderna, Inc.
Norwood, MA
Start date
Sep 27, 2022

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Job Details

The Role:

You will be responsible for design, development, and deployment for various equipment and system integration for Digital Lab Systems. This is an exciting opportunity to influence the direction and digital vision of the company as we build world class process development and testing capabilities to further our mission of delivering transformational mRNA medicine to patients. Moderna is a cloud-first Company and this role will balance building strong foundations, with implementing innovative new solutions that drive business value. With our strong pipeline, this position will play a key role partnering with our Technical Development stakeholders to enable our digital systems and processes for long term success.

Heres What Youll Do:

  • Translate system/equipment/data integration requirements from various Technical Development teams to design, develop and deploy Digital Lab Systems solutions.

  • Follow best engineering practices and well versed in good documentation practices.

  • Demonstrate your ability to rapidly learn and improve the processes critical to our stakeholders.

  • Foster a culture of innovation and collaboration within the team and with stakeholders

  • Question the status quo, leveraging both new technologies and creative solutions within existing systems

  • Apply an operational excellence mindset to help identify, devise, and recommend new opportunities to optimize current processes

Heres What Youll Bring to the Table:

  • Bachelors degree or equivalent in science, engineering, informatics, or relevant academic discipline

  • 10-15 years experience working in a combination role of automation/integration engineer in various manufacturing industries including biologics or pharmaceutical industry.

  • Experience working with various DCS/SCADA (DeltaV, Ignition, Foxboro), PLC (Rockwell AB, Schneider Electric), HMI (GE, Wonderware), MES (Syncade/PAS-X) Historian (OSISoft, Canary, Aspentech) and Lab Automation Scheduler ( BioSero Green Button Go or HighRes Cellario).

  • Experience working with various manufacturing/lab equipment or skids and integrating to either PLC, Process Control Systems, Data Historian, automated lab scheduler/orchestrator.

  • Experience working with Digital manufacturing or lab systems hosted in cloud infrastructure (AWS/Azure/hybrid) and on-premise virtual infrastructure (VMware/HyperV)

  • Working knowledge of SQL and understands performing system administration and running queries, stored procedures.

  • Working knowledge of different Digital integration standards such as OPC, MQTT, Web Services, bus technologies.

  • Working knowledge of smart, IoT and IIoT, HART, wireless HART, Foundation Fieldbus, Profibus, ASI, ethernet I/P instruments.

  • Experience with lab instruments like HPLC, analyzers, single use systems, etc.

  • Understands working with different programming languages like Visual Basic, C, C++, etc.

  • Working knowledge of ISA95, ISA88 and ISA 18.2 standard

  • Working knowledge of Digital system network topology (VLAN, subnets, Firewall updates, TCP/IP) and system architecture (client/server communication, LDAP authentication, SSO, etc.)

  • Ability to adapt to a fast paced, startup-like environment.

  • Strong communication skills (verbal and written)

  • Ownership and drive

  • A desire to be part of a high-growth, transformational company that is Bold, Relentless, Curious, and Collaborative

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

  • Highly competitive and inclusive medical, dental and vision coverage options
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
  • Family care benefits, including subsidized back-up care options and on-demand tutoring
  • Free premium access to fitness, nutrition, and mindfulness classes
  • Exclusive preferred pricing on Peloton fitness equipment
  • Adoption and family-planning benefits
  • Dedicated care coordination support for our LGBTQ+ community
  • Generous paid time off, including:
    Vacation, sick time and holidays
    Volunteer time to participate within your community
    Discretionary winter shut down
    Paid sabbatical after 5 years; every 3 years thereafter
  • Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
  • 401k match and Financial Planning tools
  • Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
  • Complimentary concierge service including home services research, travel booking, and entertainment requests
  • Free parking or subsidized commuter passes
  • Location-specific perks and extras!

Candidates should be aware that Moderna currently maintains a policy requiring all US-based employees to be fully vaccinated against COVID-19 and receive a booster shot once eligible. Newly hired employees must be vaccinated and boosted prior to their employment start date. Moderna is an equal opportunity employer and will provide a reasonable accommodation to those unable to be vaccinated or receive a booster where it is not an undue hardship to the company to do so as provided under federal, state, and local law.

About Moderna

In over 10 years since its inception, Moderna has transformed from a research-stage company advancing programs in the field of messenger RNA (mRNA), to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across seven modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for rapid clinical and commercial production at scale. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna's capabilities have come together to allow the authorized use and approval of one of the earliest and most effective vaccines against the COVID-19 pandemic.

Moderna's mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and autoimmune diseases. Moderna has been named a top biopharmaceutical employer by Science for the past seven years. To learn more, visit

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.




Moderna is advancing messenger RNA (mRNA) science to create a new class of transformative medicines for patients. Moderna’s platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, providing the Company the capability to pursue in parallel a robust pipeline of new development candidates. Moderna is developing therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases and cardiovascular diseases, independently and with strategic collaborators.

mRNA is now a turning point in the history of science, medicine, technology, even humankind itself. With this breakthrough discovery, many of the world’s biggest and most challenging medical problems are no longer a question of “how?” but merely a question of “when?”

Come with us as we pursue the uncharted reaches of possibility and make your mark on the future of medicine.


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Cambridge, MA
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