Manufacturing Operations Technician

DNA Script

DNA Script is a leading company in manufacturing de novo synthetic nucleic acids using enzymatic DNA synthesis (EDS) technology. The company aims at accelerating innovation in life science and technology through the decentralization of rapid, on demand and high-quality DNA synthesis. DNA Script's approach leverages nature's billions of years of evolution in synthesizing DNA to set a new standard for customizing nucleic acid synthesis thus accelerating discovery in genetics, genomics, and synthetic biology. Discovery disciplines with profound impacts upon humanity such as biopharma, translational genetics and even molecular information storage all start with synthetic DNA. The company has recently initiated the commercialization of its first EDS powered platform, the SYNTAX system. 

To date, DNA Script has raised over $315M of financing, with leading investors such as Coatue Management, Fidelity Management and Research, Catalio Capital Management, Casdin Capital, LSP, Bpifrance Large Ventures, Danaher, Illumina Ventures, Agilent, Merck Ventures, Sofinnova Partners, Kurma Partners, T Rowe Price, Baillie Gifford and Eurazeo. 

DNA Script also partners on technology and product development with leading organizations such as DARPA, IARPA, Moderna Therapeutics, GE Research, Illumina, the Broad Institute, Harvard University, Institut Pasteur and the French Department of Defense.

DNA Script has its research and manufacturing facilities headquartered in Paris, France, and is in the process of expanding its commercial and development teams in South San Francisco.

Opportunity and Challenges :

We are looking to assemble a team of best-in-class, innovative and passionately eager people.  We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write.” We offer the opportunity of joining a dynamic, international, and highly skilled team in a pioneering startup. Our DNA On Demand platform not only has the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impacts across biological sciences.

Responsibilities:

• Prepare buffers, solutions, and other kit components following approved protocols
• Participate in production schedule planning, adherent to the Production Schedule and escalate issues as needed
• Utilize ERP (NetSuite) to execute work orders, perform inventory transfers and receive shipments timely and accurately.
• Maintain inventory accuracy and keep the inventory discrepancy rate under 2
• Wear proper PPE, handle hazardous chemicals safely, and actively identify and address safety concerns.
• Monitor, qualify, and maintain calibration of laboratory instrumentation used for manufacturing
• Perform reagent manufacturing, logistics planning, and other tasks as assigned
• Assist in assembly and packaging of reagents and consumables for both domestic and international shipment
• Process received materials and equipment, and spare parts for inventory accuracy in NetSuite
• Manage daily shipping and return requests for all departments.
• Execute tasks under approved SOPs, document production using batch records, and contribute to improving the overall quality in operations
• Collaborate with cross-functional teams and communicate effectively across all levels.
• Assist technology transfer, batch record revision, and manufacturing scaleup
• Lead or participate in process improvement projects.
• Initiate, manage and investigate deviations and CAPAs.
• Maintain the shipping and receiving dock by moving and organizing boxes and pallets as needed.

Other abilities:

• Able to lift 40lbs weight
• The use of a personal vehicle to travel between worksites or other locations is a primary job duty

Experience:

• Bachelor’s degree in Biology, Biochemistry, Chemistry or related field is preferred.
• 1-3 years of relevant experience is preferred
• Experience working in laboratory
• Experience working with ERP system is preferred
• Experience working under GLP/GMP and following good documentation and compliance practices
• Experience with laboratory safety procedures and documentation
• Detail oriented and meticulous attention to detail
• Willingness to take/accept new responsibilities and able to work with minimal supervision.
• Demonstrated ability to work in multidisciplinary teams

Miscellaneous

• Job located in South San Francisco
• Start date: Q3 2022
• Process Length: 2-3 weeks