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Laboratory Research Associate

Frederick National Laboratory for Cancer Research
Frederick, MD
Start date
Sep 24, 2022

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Regulatory, Science/R&D, Research, Laboratory
Required Education
Bachelors Degree
Position Type
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Job Details

Laboratory Research Associate

Job ID: req3021
Employee Type: exempt full-time
Division: Applied & Development Research Program
Facility: Frederick: Ft Detrick
Location: PO Box B, Frederick, MD 21702 USA

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc.  The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.


The Frederick National Laboratory for Cancer Research (FNLCR) is a Federally Funded Research and Development Center sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. With more than 2,000 employees, the FNLCR is responsible for pursuing translational and applied biomedical research that is unique from academia, the pharmaceutical industry, or other federal contractors. The selected candidate will join the Molecular Pharmacology Branch’s (MPB) laboratory program, located at the NCI-Frederick campus, which is composed of five laboratories seeking to deliver new treatments for recalcitrant, rare, and neglected cancers through the discovery of novel targets and the evaluation of investigational therapeutics and new drug combinations using state-of-the-art approaches.

The Developmental Therapeutics Program (DTP) maintains a high-quality, cell-based screening service for characterizing anticancer activities for a range of novel entities, including synthetics, biologics, and natural products that are submitted by investigators throughout the world. The agents are tested with established cell lines and patient-derived organoids from a wide range of cancer types. The selected candidate will be responsible for following laboratory protocols to maintain a range of established cell lines and patient-derived organoids and work within the DTP cell-based cancer screening team to conduct fully automated high-throughput screens. 

This position requires a demonstrated ability to work in a fast-paced, hands-on, and collaborative environment. The position requires excellent cell culture technique, communication, and organizational skills, including detailed recordkeeping, and computer literacy. After initial training, the selected candidate is expected to perform protocols independently with minimal guidance, with accuracy, discretion, and good judgment, and will assist with the collection and analysis of data.


  • Perform routine cell culture tasks including the maintenance and passaging of cell lines and organoids and their scale-up to large batches for drug studies or cryopreservation
  • Prepare all required medias, components, and reagents used in the culture and testing of monolayer and 3D cell cultures
  • Contribute to the ordering of laboratory supplies and tracking inventory
  • Assist in the routine maintenance of general laboratory equipment
  • Perform basic data analysis and quality control evaluations
  • Perform, operate, and communicate effectively in a group, team-oriented working environment
  • The use of personal protective equipment and strict adherence to safety protocols will be required


To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

  • Possession of a Bachelor's degree from an accredited college or university (according to CHEA) in a field related to biomedical research or four (4) years equivalent experience in the appropriate field in lieu of degree
  • In addition to the education requirement, a minimum of two (2) years of experience
  • Foreign degrees will be evaluated for U.S. equivalency
  • Excellent verbal and written communication skills and a capacity to work in a team environment
  • Ability to be flexible to meet changing needs
  • Ability to work under Biosafety Level-2 conditions
  • Knowledge of Microsoft office programs (Outlook, Word, Excel, PowerPoint)
  • Ability to obtain and maintain a security clearance


Candidates with these desired skills will be given preferential consideration:  

  • Knowledge of sterile cell culture techniques
  • Knowledge of organoid cell culture
  • Experience with and ability to operate laboratory equipment
  • Familiarity with high-throughput laboratory automation experiment


  • This position is subject to working with or have potential for exposure to animal(s)
    and/or animal material(s)
  • This position is subject to working with or have potential for exposure to infectious
    material, requiring medical clearance and immunizations

Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)



A rewarding career with global impact

Whether you’re an expert in your field or just starting out, we have a career opportunity for you. We’re always looking for people to join us in fulfilling the mission of the Frederick National Laboratory: discovery, innovation, and success in the biomedical sciences.

Our team of 2,400+ scientists, technicians, administrators, and support staff work at the forefront of basic, translational, and preclinical science, with a focus on cancer, AIDS, and other infectious diseases.

We collaborate with colleagues across the National Cancer Institute, National Institutes of Allergy and Infectious Diseases, and others throughout the National Institutes of Health. We also engage with extramural investigators in academia, government and industry.

Your path to joining our team begins with the desire to work for the only national laboratory dedicated to biomedical research. Our employees share a common desire to help make a difference in cancer research and public health concerns. As you search for a career that fits your education, skills, and abilities, explore the core values that guide us and emphasize work-life balance.

Discover why joining the Frederick National Laboratory team could be the most important career step you take



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