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Principal Systems Engineer, SAP CMC

Moderna, Inc.
Norwood, MA
Start date
Sep 23, 2022

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Science/R&D, CMC
Required Education
Bachelors Degree
Position Type
Full time
Genetown, Best Places to Work
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Job Details

The Role

Reporting to the Associate Director Supply Chain Systems, the Principal Systems Engineer, SAP CMC, will implement and support SAP S/4 PP/QM/MM/LE functionality along with integration of S/4 HANA with 3rd parties application (MES / LIMS / Ariba SCC) across a pharmaceutical manufacturing environment. This position will play a key role in supporting the Supply Chain systems strategy and will collaborate cross functionally to align data, processes and technology throughout the deployment of solutions.

This is a great opportunity for someone to who has always wanted to a have a great impact on shaping the outcome of supply chain solutions in a fast-paced pharmaceutical environment.

This position is based in Norwood, MA.

Heres What Youll Do

  • Be the key point of contact for internal and external quality, internal and external manufacturing

  • Techno functional expertise in SAP S/4 QM, PP, LE and MM modules to configure and maintain world class integrations to meet current requirements and emerging pharmaceutical supply chain challenges

  • Possess expert knowledge in quality release processes for internal manufacturing, as well as external process (subcontracting process in SAP)

  • Perform business analysis and SAP ERP S/4 system support of quality, supply and manufacturing business units in a fast-paced clinical drug manufacturing environment.

  • Implement solutions within SAP S/4 system to improve internal / external quality and manufacturing processes

  • Support data analysis, program debugging and report writing.

  • Write business design documents, functional specs, configuration specs and test scripts

  • Implement SAP projects to drive continuous improvement.

  • Observe and evaluate industry trends and benchmark operations against industry standards and make recommendations on best practices

Heres What Youll Need (Minimum Qualifications)

  • Minimum 8 years of experience in the design, configuration and testing of solutions across an SAP system

  • Experience in an FDA regulated environment such as Pharma/Medical device.

Heres What Youll Bring to the Table (Preferred Qualifications)

  • Experience with drug product serialization and serialization software

  • Experience in the following submodules highly preferred

    • Manufacturing and Quality (PP-PI and QM)

      • Integration with LIMS (LabVantage)

    • Material Management (MM) & Inventory management (IM)

    • EWM and/or WM / HUM SAP modules

  • Familiarity of SAP S/4

  • Experience with proposing functional solutions to developers when writing functional specs.

  • Experience engaging with regulatory business stakeholder or regulatory agencies.

  • Familiarity with the technical integration between SAP and partner systems using middleware applications exchanging data with standards such as EDI and EPCIS

  • A desire to make an impact as part of a high-growth, transformational company that is Bold, Relentless, Curious, and Collaborative

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

  • Highly competitive and inclusive medical, dental and vision coverage options
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
  • Family care benefits, including subsidized back-up care options and on-demand tutoring
  • Free premium access to fitness, nutrition, and mindfulness classes
  • Exclusive preferred pricing on Peloton fitness equipment
  • Adoption and family-planning benefits
  • Dedicated care coordination support for our LGBTQ+ community
  • Generous paid time off, including:
    Vacation, sick time and holidays
    Volunteer time to participate within your community
    Discretionary winter shut down
    Paid sabbatical after 5 years; every 3 years thereafter
  • Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
  • 401k match and Financial Planning tools
  • Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
  • Complimentary concierge service including home services research, travel booking, and entertainment requests
  • Free parking or subsidized commuter passes
  • Location-specific perks and extras!

Candidates should be aware that Moderna currently maintains a policy requiring all US-based employees to be fully vaccinated against COVID-19 and receive a booster shot once eligible. Newly hired employees must be vaccinated and boosted prior to their employment start date. Moderna is an equal opportunity employer and will provide a reasonable accommodation to those unable to be vaccinated or receive a booster where it is not an undue hardship to the company to do so as provided under federal, state, and local law.

About Moderna

In over 10 years since its inception, Moderna has transformed from a research-stage company advancing programs in the field of messenger RNA (mRNA), to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across seven modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for rapid clinical and commercial production at scale. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna's capabilities have come together to allow the authorized use and approval of one of the earliest and most effective vaccines against the COVID-19 pandemic.

Moderna's mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and autoimmune diseases. Moderna has been named a top biopharmaceutical employer by Science for the past seven years. To learn more, visit

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.




Moderna is advancing messenger RNA (mRNA) science to create a new class of transformative medicines for patients. Moderna’s platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, providing the Company the capability to pursue in parallel a robust pipeline of new development candidates. Moderna is developing therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases and cardiovascular diseases, independently and with strategic collaborators.

mRNA is now a turning point in the history of science, medicine, technology, even humankind itself. With this breakthrough discovery, many of the world’s biggest and most challenging medical problems are no longer a question of “how?” but merely a question of “when?”

Come with us as we pursue the uncharted reaches of possibility and make your mark on the future of medicine.


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