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SEC Manager

Prometheus Biosciences
San Diego, California
Start date
Sep 21, 2022
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Job Details



SEC Manager - San Diego, CA

We’re a different kind of biotech company.  And we’re here to make a difference.


Prometheus Biosciences, Inc. (Nasdaq: RXDX), is a clinical-stage biotechnology company pioneering a precision medicine approach for the discovery, development and commercialization of novel therapeutic and companion diagnostic products for the treatment of immune-mediated diseases. 


The Company’s precision medicine platform, Prometheus360™, combines proprietary machine learning-based analytical approaches with one of the world’s largest gastrointestinal bioinformatics databases to identify novel therapeutic targets and develop therapeutic candidates to engage those targets.  Headquartered in San Diego, Prometheus Biosciences, Inc. was named Best Places to Work by Biospace, San Diego Business Journal and is a Great Place to Work-Certified™ Company. 



The SEC Reporting Manager is a newly created role and will be responsible for SEC Reporting in addition to responsibilities for technical accounting and internal controls.  This position reports to the Executive Director, Finance and Accounting and is based in San Diego, CA. 



  • SEC Reporting
  • Prepare all reports (Quarterly, Annual) as per SEC requirements (8-K, 10-Q, 10-K, and Annual Report)
  • Prepare supporting schedules and tie-out support for periodic SEC filings including items requested by internal and external auditors
  • Assist with preparation of quarterly earnings release
  • Maintain all necessary deadlines in accordance with the SEC
  • Maintain consistent contact with external auditors to ensure compliance with SEC standards
  • Draft financial reporting procedures to comply with internal control requirements
  • Technical Accounting
  • Draft technical accounting memos
  • Keep abreast of latest changes to the accounting standards
  • Internal Controls
  • Primary liaison with external internal audit consultants and auditors; provide day to day coordination and communication with accounting and finance personnel
  • Perform periodic review of certain segregation of duties analyses; advise management of results and propose solutions as appropriate
  • Perform periodic user access reviews for ERP and other relevant financial systems; investigate discrepancies, propose solutions, and advise management as appropriate
  • Assist with IT related Sarbanes Oxley compliance requirements i.e., process documentation, internal controls rationalization, controls testing, etc. as requested
  • Other
  • Responsible for reporting equity compensation and day to day management of Equity Edge software
  • Responsible for review of journal entries, as assigned
  • Take the lead on ad-hoc, project-based assignments including systems implementation and conversion tasks, as assigned


Education and Experience

  • CPA and Bachelor’s degree in Accounting or Business Administration with an Accounting focus
  • 5+ years accounting experience, with at least 2 years SEC reporting; Big 4 public accounting experience required
  • Strong knowledge of US GAAP and SEC reporting requirements
  • Biotech or life sciences industry experience strongly preferred
  • Experience with QuickBooks and Great Plains software preferred
  • Experience with Equity Edge software preferred
  • Experience with Active Disclosure software is a plus


Essential Skills and Abilities

  • Unquestionable integrity, be able to inspire trust and exhibit the highest ethical standards
  • Strong Excel skills
  • Ability to work closely with management
  • Commitment to all reporting and audit deadlines
  • Excellent communication, verbal, written and interpersonal skills
  • Sound judgment and critical thinking skills
  • Highly detail oriented and meticulous with data
  • Ability to handle multiple tasks and shift with changing priorities
  • Super organized with effective time management and ability to meet tight deadlines



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Prometheus Biosciences is a biotech company pioneering a precision medicine approach for the discovery, development, and commercialization of novel therapeutic and companion diagnostic product candidates. While our initial focus was on IBD, we're now extending beyond gastrointestinal (GI) diseases to target other autoimmune diseases.

Prometheus360TM, our powerful precision medicine platform, combines proprietary technology with the world's most comprehensive collection of IBD patient data, to translate deep, complex data into precision therapeutic and diagnostic product candidates and continually identify new drug targets and unique disease biomarkers. We're headquartered in San Diego, CA.


Find Us
(858) 824-0895
3050 Science Park Road
San Diego
United States
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