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Research Associate I - Palop Lab

Employer
Gladstone Institutes
Location
San Francisco, CA
Start date
Sep 15, 2022

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Discipline
Regulatory, Science/R&D, Research, Laboratory
Required Education
Associate Degree
Position Type
Full time
Hotbed
Biotech Bay
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Job Details

Category:Science
Lab/Area:Palop Lab

Description:

The Gladstone Institutes is an independent, not-for-profit research institution affiliated with the University of California San Francisco (UCSF), contributing to the health and well-being of all people through medical research, education, and outreach in the areas of heart disease, HIV/AIDS, and neurological disease.
Gladstone is composed of five separate institutes and approximately 400 employees. Our employees receive exceptional benefits. We are located in an award-winning building adjacent to UCSF Mission Bay Campus.
Gladstone has consistently ranked as one of the top places to work in academia in the United States.


The Palop laboratory at the Gladstone Institutes is seeking a Research Associate to provide support for projects aimed at understanding cellular, synaptic and network dysfunction in Alzheimer’s disease, epilepsy and other neurological disorders. The project is supported by a NIH-SBRI grant aimed at developing novel therapeutics to treat cognitive and network dysfunction in Alzheimer’s disease (AD) and Dravet syndrome (DS). This position will focus on preclinical evaluation in mouse models of AD and DS and will require: breeding and maintaining mouse colonies of AD and DS mouse models, dosing (injecting) cohorts of mice for treatment administration, performing behavioral and EEG experiments to assess treatment efficacy of the small molecules, and postmortem immunostaining experiments. The successful candidate will work a as part of a team but may also carry out independent experiments, including data analyses and preparation of figures. Training will be provided and prior experience in behavioral experiments, colony management, IHC, and electrophysiology is preferred but not required. This position offers the opportunity to integrate cutting edge behavioral paradigms and in vivo electrophysiology analysis with machine learning while developing novel therapeutics for Alzheimer’s disease and Epilepsy.

Applicants must hold an Associate's degree and 2+ years relevant experience or a Bachelor’s or Master’s degree in Neuroscience or related field with 1–2 years of relevant experience working with rodents. Please provide a cover letter, CV and names of 2-3 references.

Desired experience

  • Experience working with rodents, handling, dosing (injections) and genotyping.

  • Experience maintaining mouse colonies, perfusions, and preparing brain tissue for immunohistochemistry.

  • Experience with analytical and visualization software including ImageJ, Excel, Prism, Python, MATLAB, and/or SPSS.

  • Experience performing behavioral experiments in rodents.

  • Experience with multi-electrode array (MEA) recordings from brain slices, and/or electrophysiology.

  • Organized, communicative, detail-oriented, and self-motivated to perform projects independently.

  • Eager to learn, passionate about neuroscience, and ready to make meaningful contributions to science.

At Gladstone and in the Palop Laboratory, we know it takes a diverse group of empowered individuals to use science to effectively overcome disease. We are committed to creating a diverse community and cultivating a culture where every individual is respected and can succeed. We encourage applications from members of groups historically underrepresented in the sciences.


Additional Information:
  • Title and salary will be commensurate with education and experience.
  • Gladstone is an equal opportunity employer.

Company

Gladstone is an independent, nonprofit life science research organization located in the epicenter of biomedical and technological innovation in the San Francisco Bay Area. Gladstone has created a research model that disrupts how science is done, funds big ideas, and attracts the brightest minds. Gladstone Institutes leads the way for innovative research in the biomedical field. We always seek dedicated and talented individuals to join our team.

Scientists know that using a diversity of approaches is often the most efficient strategy for solving a problem. New and different perspectives engender the very innovation that Gladstone prizes. This is one of the many reasons why we value diversity at Gladstone—be that a diversity of race, culture, religion, mental or physical ability, heritage, age, gender, sexual orientation or other characteristics. Our employees hail from more than 30 countries around the globe and we seek to hire the best and brightest for our diverse team of scientists and administrators. Career opportunities are available in both our administrative offices and our research areas.

Our Benefits
Gladstone offers eligible employees—and their dependents—a comprehensive range of benefits, including health insurance, retirement savings, and professional development.

Highlights

  • Health and Retirement
    • A choice of medical plans, flexible spending account, and retirement account options that include employer contributions help you take care of your health and your future.
  • Time Away from Work
    • More than just vacation days, our paid and unpaid leave policies offer flexibility to help you confront different stages of life including maternity and paternity leave, as well as other types of family leave.
  • Professional Development
    • Gladstone encourages employees to seek the skills they need to remain at the forefront of their profession. By supporting professional development workshops and continuing education, Gladstone provides employees with the resources they need to evolve in their role and in their career.
  • Gladstone Cares
    • A specially selected suite of benefits to support you in and out of the workplace. Includes resources for dealing with the many stages of life to specific coverage for family planning, and back-up child or elder care coverage.
Find Us
Website
Location
1650 Owens Street
San Francisco
California
94158
United States
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