Associate Engineer, Process and Product Development (MSAT)

Company Background:

Century Therapeutics is developing novel allogeneic living cell products for oncology that overcome the limitations of current cell therapies. Century's genetically-engineered, universal iPSC-derived immune effector cell products are designed to specifically target hematologic and solid tumor cancers. Our commitment to developing off-the-shelf cell therapies will expand patient access and provide an unparalleled opportunity to advance the course of cancer care.

Century's foundational technology is built on induced pluripotent stem cells (iPSCs) that have unlimited self-renewing capacity. This enables complex cellular engineering to produce controlled cell banks of modified cells that can be expanded and differentiated into desired immune effector cells, which can supply vast amounts of allogeneic, homogeneous therapeutic products. This platform differentiates Century from other approaches that utilize non-renewable donor-derived cells.

Role

The Associate Engineer will be responsible for implementing, developing, and executing manufacturing processes for Century's cellular therapy programs. The candidate will be expected to receive process tech transfers, implement them into a GMP manufacturing facility, and be a hands-on operator for the Phase I manufacturing campaign. This role will also be responsible for ongoing process development on these Phase I programs, including scale up in bioreactors, scale up of the downstream process, and characterization of the entire process. This role requires extensive collaboration with internal and external teams. The successful candidate will need a strong scientific background, interpersonal skills, and ability to work collaboratively with other groups across organizations.

This role is based in Branchburg, NJ.

Responsibilities:

• Receive tech transfers from other sites.
• Implement and run cell processes into GMP manufacturing.
• Assist in developing, executing, and documenting process development experiments.
• Scale up current processes as necessary
• Support manufacturing as SME, including troubleshooting.
• Identify areas for process improvements and work cross functionally towards implementing changes.
• Operate and maintain lab equipment.
• Author technical documents (e.g. batch records, SOPs, reports, etc.).
• Support preparation of CMC documents for regulatory filings.
• Foster a collaborative and scientifically rigorous team culture.

Qualifications:

• A BS or MS degree in biochemical, chemical, biomedical engineering or other related field.
• 4-6 years for BS, or 2-4 years for MS, of relevant professional experience.

Requirements:

• Strong scientific background.
• Knowledge of and experience with cell culture and aseptic technique.
• Lab experience in a research or industry setting.
• Process development experience is strongly preferred.
• Excellent oral and written communication skills.
• Knowledge of cGMPs is a plus.

Century Therapeutics Inc. is an Equal Employment Opportunity/Affirmative Action Employer - Minority/Female/Disability/Veteran. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or veteran status or any other characteristic protected by federal, state, or local law.