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Research Associate II, CLIA Next Gen Sequencing

Frederick National Laboratory for Cancer Research
Frederick, MD
Start date
Sep 8, 2022

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Regulatory, Research/Documentation, Science/R&D, Research
Required Education
Bachelors Degree
Position Type
Full time
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Job Details

Research Associate II, CLIA Next Gen Sequencing

Job ID: req2951
Employee Type: exempt full-time
Division: Clinical Research Program
Facility: Frederick: Ft Detrick
Location: PO Box B, Frederick, MD 21702 USA

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc.  The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.


The Molecular Characterization Laboratory (MoCha) is part of Leidos Biomedical Research’s Clinical Research Directorate (CRD) at the Frederick National Laboratory for Cancer Research. The MoCha Laboratory is responsible for providing high-level research in support of the NCI-Cancer Diagnostics Program (CDP) within the Division of Cancer Treatment and Diagnosis (DCTD). MoCha is charged with the development and application of genomic assays for use in medical research and diagnostics for DCTD-sponsored national extramural clinical trials.


  • Performs genomics research and/or assay development in collaboration with others for projects
  • Makes detailed observations, analyzes data and interprets results
  • Investigates, creates and develops new methods and technologies for project advancement
  • Maintains high level of professional expertise through familiarity with scientific literature
  • May participate in scientific conferences and contribute to scientific journals
  • May be responsible for identifying patentable inventions
  • May act as principal investigator in conducting own experiments
  • Exercises independent judgment in developing and/or modifying methods and techniques for solving scientific problems
  • Performs molecular assays by adherence to SOPs
  • Develops new assays and applies the methods/assays utilizing sound scientific judgement
  • Writes SOPs and performs formal reporting of research data, including presentations and/or scientific publications
  • Maintains knowledge of the most recent literature and scientific presentations relevant to projects
  • Maintains essential laboratory supplies and monitors equipment for optimum performance
  • May be willing to assume supervisory roles as needed


To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below: 

  • Possession of Bachelor’s degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) or four (4) years relevant experience in lieu of degree. Foreign degrees must be evaluated for U.S. equivalency
  • In addition to the education requirement, a minimum of five (5) years of experience with next generation sequencing library creation and sequencing and/or molecular biology techniques
  • Ability to obtain and maintain a security clearance 


Candidates with these desired skills will be given preferential consideration:  

  • Experience in NGS genomic profiling assays
  • Experience in genomic assay development and workflow automation
  • Familiarity with clinical oncology studies and other protocol-driven clinical research
  • Experience working in clinical laboratory testing


  • Proficient with Microsoft Office programs (Word, Excel, Powerpoint, Access)
  • Strong technical skills in molecular biological and genomic assays
  • Ability to independently evaluate the suitability and quality control of research or production assays or tests, develop and follow SOPs, and analyze and report data
  • Ability to track information in a large cohort of samples and monitor progress of multiple projects
  • Adequate computer skills to document, organize, and present experimental data
  • Strong critical thinking and problem solving skills
  • Ability to communicate effectively, both verbally and in writing 


  • This position is subject to working with or have potential for exposure to infectious
    material, requiring medical clearance and immunizations

Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)



A rewarding career with global impact

Whether you’re an expert in your field or just starting out, we have a career opportunity for you. We’re always looking for people to join us in fulfilling the mission of the Frederick National Laboratory: discovery, innovation, and success in the biomedical sciences.

Our team of 2,400+ scientists, technicians, administrators, and support staff work at the forefront of basic, translational, and preclinical science, with a focus on cancer, AIDS, and other infectious diseases.

We collaborate with colleagues across the National Cancer Institute, National Institutes of Allergy and Infectious Diseases, and others throughout the National Institutes of Health. We also engage with extramural investigators in academia, government and industry.

Your path to joining our team begins with the desire to work for the only national laboratory dedicated to biomedical research. Our employees share a common desire to help make a difference in cancer research and public health concerns. As you search for a career that fits your education, skills, and abilities, explore the core values that guide us and emphasize work-life balance.

Discover why joining the Frederick National Laboratory team could be the most important career step you take



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8560 Progress Drive
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