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Research Associate II

Frederick National Laboratory for Cancer Research
Bethesda, MD
Start date
Sep 7, 2022

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Regulatory, Research/Documentation, Science/R&D, Research
Required Education
Bachelors Degree
Position Type
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Job Details

Research Associate II

Job ID: req2824
Employee Type: exempt full-time
Division: Applied & Development Research Program
Facility: NIH
Location: NIH Campus 9000 Rockville Pike, Bethesda, MD 20892 USA

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc.  The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.


The Frederick National Laboratory for Cancer Research (FNL) is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by the prime contractor Leidos Biomedical Research, Inc. FNL is responsible for pursuing a unique mission in translational and applied biomedical research that is unsuitable for academia, the pharmaceutical industry, or other federal contractors.  The selected candidate will join the National Clinical Target Validation Laboratory (NCTVL) located at the NIH Bethesda campus. 

The NCTVL serves as a clinical pharmacodynamic biomarker validation and testing center for the NCI’s Division of Cancer Treatment & Diagnosis (DCTD) and is a key component in the clinical pharmacodynamics (PD) program at the Frederick National Laboratory for Cancer Research.  NCTVL works closely to convert newly developed and validated assays of biomarkers of drug mechanism of action into clinical assays, and works closely with NCI clinicians and investigators to use the validated clinical assays to analyze patient specimens from early clinical trials and report assay results to inform the trials and confirm drug mechanisms of action (MOA) of the investigational agents in patients.


  • Perform quantitative multiplex immunoassays to support the clinical PD program
  • Work collaboratively within a team environment in sample collection, processing, testing and data collection/analysis and reporting
  • Provide lab support for critical reagent manufacturing, assay development, transfer, validation and testing including
  • Preclinical model studies


To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

  • Possession of a (CHEA) Bachelor's degree from an accredited college/university in a field related to biomedical research. Foreign degrees will be evaluated for U.S. equivalency
  • In addition to educational requirements, a minimum of five (5) years of related experience in multiplex biomarker testing
  • Excellent basic laboratory skills in biomedical R & D
  • Good written and oral communication skills, excellent computer skills with Word/Excel, follow existing protocols and willingness to explore new technologies 
  • Ability to obtain and maintain a security clearance 


Candidates with these desired skills will be given preferential consideration: 

  • Experience performing multiplexed immunoassays with Luminex platform in a clinical or preclinical research program
  • Experience with IVD assay development and clinical specimen testing experience


  • This position is subject to working with or have potential for exposure to animal(s)
    and/or animal material(s)
  • This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations.


Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)



A rewarding career with global impact

Whether you’re an expert in your field or just starting out, we have a career opportunity for you. We’re always looking for people to join us in fulfilling the mission of the Frederick National Laboratory: discovery, innovation, and success in the biomedical sciences.

Our team of 2,400+ scientists, technicians, administrators, and support staff work at the forefront of basic, translational, and preclinical science, with a focus on cancer, AIDS, and other infectious diseases.

We collaborate with colleagues across the National Cancer Institute, National Institutes of Allergy and Infectious Diseases, and others throughout the National Institutes of Health. We also engage with extramural investigators in academia, government and industry.

Your path to joining our team begins with the desire to work for the only national laboratory dedicated to biomedical research. Our employees share a common desire to help make a difference in cancer research and public health concerns. As you search for a career that fits your education, skills, and abilities, explore the core values that guide us and emphasize work-life balance.

Discover why joining the Frederick National Laboratory team could be the most important career step you take



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