Senior Director / Vice President, Translational Medicine

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Adicet Bio, Inc is a clinical stage biotechnology company discovering and developing allogeneic gamma delta T cell therapies for cancer. We are advancing a pipeline of “off-the-shelf” gamma delta T cells, engineered with chimeric antigen receptors (CAR) and T cell receptor-like antibodies (TCRL), to enhance selective tumor targeting, facilitate innate and adaptive anti-tumor immune response, and improve persistence for durable activity in patients. Our approach to activate, engineer and manufacture allogeneic gamma delta T cell product candidates derived from the peripheral blood cells of unrelated donors allows us to generate new product candidates in a rapid and cost-efficient manner. For more information, please visit our website at http://www.adicetbio.com.

SENIOR DIRECTOR / VICE PRESIDENT, TRANSLATIONAL MEDICINE

We are seeking a Senior Director / Vice President of Translational Medicine to lead the Company’s translational medicine activities. The individual will define and implement preclinical and clinical translational and biomarker strategies for ?d T cell-based product candidates entering clinical development, and lead the execution of these strategies in clinical trials across the entire pipeline.

Responsibilities:

• Manages translational and biomarker strategies to progress Adicet Bio’s programs efficiently to the clinic
• Procures and manages vendors to implement biomarker assay development and to perform biomarker analysis
• Manages the development of clinical companion diagnostic tests
• Establishment and analytical validation of quantitative clinical biomarkers for immunological and CAR-T assessments
• Understands project timelines and deliverables, and plans/coordinates project work accordingly with departmental, functional, and other stakeholders
• Prepares and reviews translational medicine sections of IBs, INDs, abstracts, manuscripts, and technical reports
• Contributes to scientific and strategy discussions to advance and enhance Adicet Bio’s platform and product candidates
• Closely mentors junior scientists to further develop talent within the group

Requirements:

• PhD with a minimum of 10 years of relevant experience, preferably in biotechnology or pharmaceutical sectors. MD desirable
• Strong background in cellular immunology and immuno-oncology, with an understanding of the tumor microenvironment of solid tumors
• Experience in in-depth characterization of T/NK cells and/or CAR T/NK cell products is preferred
• Experience in developing clinical companion diagnostic tests is highly desirable
• Proven and demonstrated record for establishing and executing quantitative clinical biomarker endpoints and assays in GCP setting.
• Strong team player with the ability to work in cross-functional teams
• Excellent interpersonal, verbal, and written communication skills
• Translational research experience is preferred

Adicet Bio requires all workers to be fully vaccinated against COVID-19, including the booster dose.

Benefits:

Adicet Bio offers both comprehensive benefits and Paid Time (PTO) plans for employees, which begin on the first day of employment, as well as the opportunity to work in a growing, dynamic environment.

Adicet Bio is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.