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Research Associate I, Molecular Biology

Employer
AnaptysBio, Inc.
Location
San Diego, CA
Start date
Sep 5, 2022

View more

Discipline
Regulatory, Science/R&D, Biology, Molecular Biology
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Beach

Job Details

Job Type Full-time

Position Summary

This position is responsible for the processing and preparation of samples to generate libraries for next generation sequencing, and possibly participate in other molecular biology activities such as cloning of antigens, antibodies and their mutational variants.

Essential Functions

  •  Prepare and process samples for next generation sequencing
  •  Perform PCR, DNA mini-, midi-, maxi-prepping procedures
  •  Analyze DNA sequences 
  •  Maintain and archive DNA clones, and bacterial glycerol stocks
  •  Organize, summarize and present data and results at department and project team meetings
  •  Help with general duties, including washing glassware, autoclaving and placing orders
  •  Maintain detailed and well-organized record of experiments carried out
  •  Develop an expanding technical and theoretical knowledge base in molecular biology with a growing understanding of the scientific literature in relevant areas of research
  •  Maintain familiarity with literature to propose and implement improved procedures and protocols, and to aid in problem solving
  •  Follow and adhere to SOPs and laboratory safety regulations 

Supervisory Responsibilities

None

Requirements

Qualifications

Education & Experience: 

  •  Theoretical knowledge typically achieved through a related four-year college experience, such as a Bachelor’s degree in Molecular Biology or related scientific field

Knowledge and Competencies: 

  •  Knowledge of standard molecular biology techniques such as PCR and cloning methodologies, including vector and primer design
  •  Practical knowledge of protein expression vectors (promoter, transcriptional signals, etc.) and have the ability to analyze DNA and protein sequences 
  •  Knowledge of tissue culture and mammalian cell transfection procedures is a plus
  •  Knowledge of DNA analysis software programs such as Sequencher, DNAStar or their equivalent, and with Microsoft Office (Word, Excel, Powerpoint) 
  •  Ability to communicate clearly, and to report and present experimental results and analysis to company colleagues
  •  Effective interpersonal skills, including both written and oral communication skills
  •  Ability to multi-task, organize multiple assignments, and work simultaneously on at least 2 projects 
  •  Ability to work effectively as a team player in a complex, changing environment
  •  Self-motivated, independent, and results-oriented 
  •  Team player, intensely committed to success and getting the job done well in a highly dynamic environment
  •  Ability to learn and follow protocols
  •  Strong analytical and organizational skills, with high attention to details

Physical Demands

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

While performing the duties of this job, the employee is regularly required to sit and talk or hear. The employee frequently is required to use hands to finger, handle, or feel. The employee is occasionally required to stand, walk, and reach with hands and arms. The employee must occasionally lift and/or move up to 10 pounds. Specific vision abilities required by this job include close vision and ability to adjust focus in order to read.

Work Environment

The work environment characteristics are representative of those an employee encounters while performing the essential functions of this job, typically in an open office and laboratory environment. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

The noise level in the work environment is usually moderate.

This position requires working with biological and/or chemical hazards

 All qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or other legally protected status.  

Company

AnaptysBio is a clinical-stage biotechnology company focused on delivering innovative immunology therapeutics. We are developing immune cell modulators, including two checkpoint agonists in clinical-stage development, for autoimmune and inflammatory disease: rosnilimab, our PD-1 agonist program in a Phase 2 trial for the treatment of moderate-to-severe rheumatoid arthritis; and ANB032, our BTLA agonist program, currently in a Phase 2b trial for the treatment of moderate-to-severe atopic dermatitis. Our preclinical immune cell modulator portfolio includes ANB033, an anti-CD122 antagonist antibody for the treatment of autoimmune and inflammatory diseases. In addition, AnaptysBio has developed two cytokine antagonists available for out-licensing: imsidolimab, an anti-IL-36R antagonist, in Phase 3 for the treatment of generalized pustular psoriasis, or GPP, and etokimab, an anti-IL-33 antagonist for the treatment of respiratory disorders that is Phase 2/3 ready. AnaptysBio has also discovered multiple therapeutic antibodies licensed to GSK in a financial collaboration for immune-oncology, including an anti-PD-1 antagonist antibody (Jemperli (dostarlimab-gxly)), an anti-TIM-3 antagonist antibody (cobolimab, GSK4069889) and an anti-LAG-3 antagonist antibody (GSK4074386).

Our corporate vision is to transform patient health by delivering innovative immunology therapeutics. Find out more about us by following us on Twitter.

 

CONNECT

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Company info
Website
Phone
858-362-6295
Location
10770 Wateridge Circle
Suite 210
San Diego
California
92121
United States

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