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Senior Research Associate

Employer
BioMarin Pharmaceutical Inc.
Location
San Rafael, California
Start date
Sep 4, 2022

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Discipline
Regulatory, Research/Documentation, Science/R&D, Research
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Bay
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Job Details

BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind.

BioMarin’s Research & Development group is responsible for everything from research and discovery to post-market clinical development. Research & Development involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with rare diseases. Come join our team and make a meaningful impact on patients’ lives.

We are searching for a self-motivated Senior Research Associate with 6-8 years of hands-on laboratory experience.

The successful candidate will work in the non-oncology hematology group to develop and use molecular and biochemical assays to measure pharmacodynamics, pharmacokinetics, immunogenicity, and biomarkers of new therapeutics. The Senior Research Associate will contribute to 2-3 different pre-clinical research projects to assess pharmacokinetics efficacy and mechanism of action. 

Responsibilities include:

  • Receive, organize, and process animal tissue samples such as the preparation of protein extracts and DNA/RNA extraction
  • Utilize molecular biology techniques including qPCR and ddPCR
  • Optimize, troubleshoot, and perform biochemical assays such as ELISA, enzyme activity and Western Blot
  • Perform data analysis and present results in group and project team meetings
  • Thoroughly document procedures and results
  • Assist with lab organization as needed

 Skills:

  • Experience in DNA/RNA purification preferably from animal tissues
  • Perform analytical assays such as PCR, ELISA and Western Blot
  • Ability to follow protocols, design and perform experiments, propose data interpretation
  • Willingness to learn new molecular and biochemical procedures
  • The position requires organizational skills, attention to detail, self-motivation, teamwork, and dedication to quality in a fast-paced setting
  • Committed to overcome challenges and ability to troubleshoot
  • Excellent written and verbal communication to occasionally present at group and team meetings
  • Proficient in basic IT skills including the use of Excel, PowerPoint, Word
Education:

Bachelor’s degree in molecular biology, biochemistry or a related scientific field and at least 6-8 years of relevant experience OR Master's degree with at least 4-6 years of relevant experience.



PLEASE NOTE: Absent a Medical or Religious reason that prohibits vaccinations, all our incoming employees must be vaccinated for COVID-19.

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, sexual orientation, national origin, disability status, protected veteran status, or any other characteristic protected by law.

Company

BioMarin is a global biotechnology company dedicated to transforming lives through genetic discovery. In 1997, the company was founded to make a big difference in small patient populations, focusing on giving much-needed attention to the underserved communities of those with rare diseases. BioMarin sought to help patients whose voices could not always be heard and treat conditions that were not always in mainstream medical conversations. Throughout its history, BioMarin has worked tirelessly to make a difference by pursuing bold science. The company’s first approved therapy was inspired by a father who refused to accept there was no therapy for his son’s rare diagnosis. That relentless pursuit to change the course of his son’s future through the power of science is at the core of who BioMarin is today.

Through the company’s expertise in genetics and molecular biology, BioMarin has developed eight first or best-in-class targeted therapies that address the root cause of the conditions it seeks to treat, helping to better the lives of those struggling with rare genetic disease. The company’s purposeful and scientifically precise team of physicians and scientists has honed each treatment modality to seek transformative therapies.

Now, BioMarin seeks to make an even greater impact by applying the same science-driven, patient-forward approach that propelled the last 25 plus years of drug development to larger genetic disorders, as well as genetic subsets of more common conditions. Each drug candidate pursued is guided by a fundamental understanding of the genetics and underlying biology of the condition it will address. The company believes that applying its knowledge to make a transformative impact is not just a calling, but an obligation to those who will benefit most. The more innovative solutions developed, the more lives BioMarin can impact.

Company info
Website
Location
California
United States
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