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Staff Manufacturing Engineer, Instruments and Systems

Menlo Park, CA
Start date
Aug 18, 2022

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Manufacturing & Production, Manufacturing/Mechanical
Required Education
Bachelors Degree
Position Type
Full time
Biotech Bay
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Job Details

Please be aware that, as a condition of employment, proof of COVID vaccination is required for all U.S.-based employees (subject to limited exceptions).  To ensure the health and safety of all PacBio employees and our prospective candidates, we have instituted a virtual interview and onboarding experience.

Title: Staff Manufacturing Engineer, Instruments and Systems
Location: Menlo Park, CA

PacBio (NASDAQ: PACB) is a premier life science technology company that is designing, developing, and manufacturing advanced sequencing solutions to help scientists and clinical research resolve genetically complex problems.  Our mission is to enable the promise of genomics to better human health. Genomics is core to all biological processes, and our advanced genomics tools provide scientists and clinical researchers the insights to better understand biology and health.  We are now entering the century of biology and genomics is at the heart of the next revolution.  Become part of the new paradigm in gene sequencing and help shape the future of genomic study by joining the PacBio team.

The instrument manufacturing team is looking for a highly motivated and capable manufacturing engineer to support a wide range of production ramp and support activities.


  • Instrument builds, troubleshooting, and process definition.
  • Investigate and resolve a wide range of issues at our contract manufacturers and on our manufacturing floor (optics, robotics, SW/FW, etc.)
  • Define new manufacturing processes and improve new ones
  • Define and improve automated test
  • Support general manufacturing processes including BOM structuring, non-conformance troubleshooting, tooling development, failure analysis and process improvements
  • Maintaining and establishing ISO/FDA compliant processes.
  • Support ongoing quality improvements
  • Other duties as required

Position Requirements:

  • Typically requires a minimum of 8 years of related experience with a Bachelor's degree; or 6 years and a Master's degree; or a PhD with 3 years experience.
  • Degree in engineering, computer science, or related.
  • 5+ years of hands-on experience in a complex instrumentation manufacturing environment.
  • Software familiarity: Python scripting, XML / HTML markup, Visual studio experience, C# a plus.
  • Computer competency / OS familiarity: Understand network configuration / RAID setup / IPMI / BIOS; Experience working in a linux environment. Basic navigation a must, shell scripting a plus.
  • Hardware familiarity: Experience working with mechanical systems, troubleshooting motion, evaluating root cause to hardware / software; PCBA familiarity, load firmware, troubleshoot signals using DMM / oscilloscope; Optomechanical troubleshooting, past laser power / alignment measurement + troubleshooting a plus.
  • Effective analytical problem solving, judgment and decision-making skills.
  • Be able to navigate PLM software: Understand BOM structure, Find and read cable / electrical / mechanical diagrams; Experience releasing parts or generating change orders a plus; Agile PLM software a plus.
  • Ability to work independently and with little management oversight.
  • Excellent communication skills (both writing and verbal).
  • Ability to meet deadlines while successfully managing several projects in parallel.
  • Working knowledge of ISO 9001 and ISO 13485 Quality Management System (QMS) and good manufacturing practices (GMP).

All listed tasks and responsibilities are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional tasks and responsibilities.
All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability, gender identity, and sexual orientation.




At PacBio, our mission is to enable the promise of genomics to better human health.

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Find Us
1305 O'Brien Drive
Menlo Park
United States
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