Principal Research Associate, Islet Cell Therapy

JOB PURPOSE

Sana Biotechnology is seeking a creative and highly motivated individual to join our Cell Therapy – Islet Beta Cell team. You will be responsible for advancing the -omics pipelines by generating and executing crucial research material and experiments to support the clinical candidate, while working closely with other members of the Cell Therapy, Process Development, and In Vivo teams. You will report to the Senior Scientist, Islet Beta Cell Therapy.

DUTIES AND RESPONSIBILITIES

• Plan, design, and execute multiple experiments in parallel
• Work with complex cell populations to generate DNA, RNA libraries
• Build capabilities, using gold-standard library generation methods
• Work closely with other members of the Beta Cell Therapy and Process Development teams to share and apply knowledge advances
• Review and present data cross-functionally at group meetings and larger forums
• Comply with standard laboratory practices and company policies, including strict notebook documentation and biosafety policies

QUALIFICATION

• M.S. in biotechnology, stem cell, molecular biology, -omics, cell differentiation or related discipline with 2 years of relevant industry laboratory experience, with a focus towards cell therapy and/or high-throughput assays
• Demonstrated knowledge in mammalian stem cell culture and differentiation
• Proactively able to design and execute experiments
• Excellent bench skills and high standards for data integrity and quality
• Adherence to rigorous standards of good lab practices, safety, and documentation

What will differentiate you from the crowd

• Knowledge and expertise in single cell RNA sequencing
• Scientific curiosity and drive
• Experience in molecular biology, including PCR, RT-qPCR, Gibson/Golden Gate assembly, library barcoding
• Computational biology experience
• Strong communication skills

WORKING CONDITIONS

This is a laboratory bench role that may require occasional work in the weekend. No regular travel required.

What you should know

• Working safely in person on a predictable and regular in-person basis is an essential job function for this position, and the Company requires that all individuals working in-person be fully vaccinated against COVID-19, including receipt of a vaccine booster shot if recommended by the CDC

How we work together

• Lead from every seat – we seek to understand, act with honesty, and engage in the crucial conversations
• Thrive as a team – we hire amazing people, are intensely curious, and cultivate inclusion and personal connectivity
• Make it happen – we value vigorous debate, alignment around our decisions, and resilient execution

Get to know us

At Sana, we believe that a diverse workforce strengthens us as a company and helps us to achieve our mission to meaningfully change the outcome of many human diseases. This belief is a pillar of our business and is critical to our success. Our goal is that Sana is the place for talented people to bring their authentic selves to work, to have a great career and to deeply, positively impact patients.

Core to our values, we believe there is nothing more important than the health and wellness of you and your family. For benefit eligible employees, we cover 100% of the cost for employee health coverage and offer generous time-off, parental leave, short- and long-term disability, employer paid basic life insurance,  additional voluntary life insurance protection, financial wellness programs including financial planning resources, a 401(k) Plan with an immediately vested employer match, Tuition Reimbursement and Student Loan Repayment, Employee Stock Purchase Plan, commuter subsidy and a variety of wellness offerings to support each person individually.

We are committed to providing a workplace free of discrimination and harassment based on race, color, religion, age, gender, national origin, ancestry, physical or mental or sensory disability (including the use of a trained guide dog or service animal by a person with a disability), genetic information, actual or perceived HIV or Hepatitis C infection, medical condition (cancer or a record or history of cancer and genetic characteristics), marital status, sexual orientation, sexual preference, pregnancy (including childbirth and related medical conditions), disability, veteran status, political ideology, social class (including caste/caste identity), taking or requesting statutorily protected leave, status as a victim of domestic violence, sexual assault or stalking, or any other basis prohibited by applicable law.

To perform this job successfully, you must be able to perform each job responsibility satisfactorily. The job description listed above is representative of the knowledge, skills, and/or abilities required for this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the functions described above.