This job has expired

You will need to login before you can apply for a job.

Scientist I/II, Formulation & Fill/Finish (CONTRACT)

Employer
Sangamo Therapeutics, Inc.
Location
Brisbane, CA
Start date
Aug 14, 2022

View more

Discipline
Science/R&D, Biotechnology
Required Education
Bachelors Degree
Position Type
Contract
Hotbed
Biotech Bay
You need to sign in or create an account to save a job.

Job Details

Manager: Associate Director, Formulation & Fill/Finish
Department: Formulation & Fill/Finish
Location: Brisbane

Sangamo Therapeutics is a genomic medicine company building value with cutting-edge work across four distinct but complementary technology platforms – gene therapy, cell therapy, in vivo genome editing, and in vivo genome regulation. At Sangamo, we are passionate in developing genomic medicines to transform the lives of patients with serious diseases. We transform lives by building a robust, sustainable, differentiated, innovative, and high value genomic medicine pipeline that addresses patients with life-limiting conditions. Sangamo takes pride in being the first to edit endogenous human genes, first to treat patients with gene edited T cells, and first to treat patients with in vivo genome editing. Our top priority is to meet the needs of patients with commitment and compassion. Sangamo is a company where individuals can flourish, grow, and develop their expertise.

We are seeking top talent to join our team. Let’s build a better future together.


JOB SUMMARY:   
Sangamo Therapeutics is seeking a highly motivated individual with drug product formulation and process development experience to contribute to the development of best-in-class viral vector and cell therapy products. The successful candidate will be responsible for the formulation and DP process development of clinical candidates, design and execute process characterization/validation studies, lead technical process transfer to internal and external manufacturing sites in support of clinical development and commercialization of Sangamo’s internal and partnered programs. They will operate in a matrixed environment and collaborate successfully with colleagues within Technical Operations and cross-functionally with clinical, external manufacturing, supply chain and commercial groups to drive product and process excellence. This individual will manage & supervise team supporting program work packages and deliverables.


ESSENTIAL FUNCTIONS: 

  • Plan, design and execute univariate/multivariate studies to develop robust and manufacturable formulations and DP processes
  • Process data, compile results, report and communicate study findings
  • Develop and implement novel biochemical and biophysical methods suitable for cell and gene therapy product characterization.
  • Lead and/or participate in CMC/project teams for functional representation as well as support teams’ objectives and project deliverables.
  • Author and review technical protocols and reports to document study findings in support of Investigational New Drug (IND), IND amendments, BLA, as well as global marketing application submissions.
  • Partner with internal/external manufacturing and quality for process improvement, transfers, compilation and review of batch records, master production records and technical support to resolve investigations, deviations, corrective/preventative actions.
  • Excellent communication and interpersonal skills, with proven ability to work effectively in cross-functional teams to meet project milestone and timelines.


EDUCATION, EXPERIENCE AND SKILLS REQUIREMENTS:

  • BS/MS/PhD degree in biochemistry, pharmaceutical sciences, biochemical engineering, or related discipline.
  • 1-3 years of laboratory experience in biotechnology or pharmaceutical industry.
  • Experience with biologics formulation development, DP process design and manufacturing Fill/Finish is highly desirable, however, academic experience related to cell culture, analytical chemistry, viral vectors, or gene therapy will be considered.
  • Proficiency with applying chromatographic (HPLC, UPLC, column chromatography) methods, capillary electrophoresis and biophysical techniques (UV-vis, DLS, CD, FTIR, DSC, AUC, Fluorescence, particle analysis, etc.) for formulation characterization
  • AAV gene therapy, Cell Therapy & Gene Editing experience is desirable
  • Sound understanding of statistical methods and data analysis tools (e.g. JMP).
  • Team player, with good interpersonal and organizational skills.


Sangamo is an equal opportunity employer
Sangamo is committed to fostering belonging for all employees and embraces diversity, equity, and inclusion in recruiting and hiring.  All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual’s race, color, sex, gender identity, gender expression, religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws

Commitment to Safety
Sangamo requires all U.S. workers to be fully vaccinated against COVID-19 as of their start date.  This requirement is a condition of employment at Sangamo, and it applies regardless of location or classification of role.  If you are unable to receive the vaccine & booster, you will have an opportunity to request a reasonable accommodation consistent with applicable laws. 

Note to External Recruiters: We do not accept unsolicited resumes from any source other than from the candidates themselves.

Company

Sangamo Therapeutics is a genomic medicine company building value with cutting-edge work across four distinct but complementary technology platforms – gene therapy, cell therapy, in vivo genome editing, and in vivo genome regulation. At Sangamo, we are passionate in developing genomic medicines to transform the lives of patients with serious diseases. We transform lives by building a robust, sustainable, differentiated, innovative, and high value genomic medicine pipeline that addresses patients with life-limiting conditions. Sangamo takes pride in being the first to edit endogenous human genes, first to treat patients with gene edited T cells, and first to treat patients with in vivo genome editing. Our top priority is to meet the needs of patients with commitment and compassion. Along with our commitment to science and to our patients, we also endeavor to create an inclusive environment that promotes and values diversity. Sangamo is a company where individuals can flourish, grow and develop their expertise.

We are seeking top talent to join our mission. Let’s build a better future together.

Stock Symbol: SGMO

TwitterFacebook

 

Find Us
Website
Phone
(510) 970-6000
Location
7000 Marina Blvd
Brisbane
CA
94005
United States
You need to sign in or create an account to save a job.

Get job alerts

Create a job alert and receive personalized job recommendations straight to your inbox.

Create alert