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Senior Research Associate, In Vivo Pharmacology

Sana Biotechnology
Cambridge, MA
Start date
Aug 12, 2022

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Regulatory, Science/R&D, Research, Pharmacology
Required Education
Associate Degree
Position Type
Full time
Genetown, NextGen Bio
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Job Details

About the role

As a Senior Research Associate within the In Vivo Pharmacology group, you will have three primary responsibilities: (1) execute in vivo studies to support gene therapy and cell therapy research programs, (2) perform in vitro work related to in vivo studies, and (3) to support unmet needs across the Pharmacology and Toxicology organization. You will report to a Principal scientist on the in vivo pharmacology team.

What you'll do
  • Work with study lead to execute in vivo studies
  • Support tissue collection and processing for downstream assays including flow cytometry, RNA seq, ddPCR, ELISA, Luminex, MSD, and histology
  • Support in vitro work (e.g. cell culture) to complete in vivo studies
  • Diligently record data and analyses using proper software (e.g. Softmouse, Graphpad), electronic notebook (Benchling)
  • Monitor and complete multiple in vivo studies in collaboration with team members ensuring dosing, sampling, harvesting and implementation of study activities
  • Analyze data and create study reports in collaboration with partner scientists
  • Present study design and data interpretation at internal group, department or Project Team meetings and present externally at relevant scientific meetings
  • Provide mentorship and guidance to junior associates
What we're looking for
  • Bachelor's degree in a scientific discipline with 4+ years of laboratory experience in the biotech or pharma industry
  • Expertise in basic laboratory techniques and functions is required as is proficiency in common office software (typically Microsoft Word, Excel (can maintain complex spreadsheets), PowerPoint, Graphpad, FlowJo)
  • Experience developing in vitro and in vivo assays and deploying these methods at scale in a collaborative research environment
  • Experience with the isolation and culture of mammalian cell lines and primary cells with demonstrated competence in sterile cell culture technique and standard laboratory procedures
  • Experience working with pre-clinical in vivo studies or models
  • Proficiency with standard molecular biology and cell biology techniques (RNA isolation and reverse-transcription, qPCR, protein analysis, ELISA, cell co-culture, cell staining for Flow Cytometry and Lentivirus transduction)
  • Excellent record keeping and data documentation skills
  • Excellent oral and written skills
What will separate you from the crowd
  • Background in CART, bispecific or other T or NK cell-targeted immunotherapies
What you should know
  • Working safely in person on a predictable and regular in-person basis is an essential job responsibility for this position, and we require that all individuals working in-person be fully vaccinated against COVID-19, including receipt of a vaccine booster shot if recommended by the CDC

How we work together

  • Lead from every seat – we seek to understand, act with honesty, and engage in the crucial conversations
  • Thrive as a team – we hire amazing people, are intensely curious, and cultivate inclusion and personal connectivity
  • Make it happen – we value vigorous debate, alignment around our decisions, and resilient execution

Get to know us

At Sana, we believe that a diverse workforce strengthens us as a company and helps us to achieve our mission to meaningfully change the outcome of many human diseases. This belief is a pillar of our business and is critical to our success. Our goal is that Sana is the place for talented people to bring their authentic selves to work, to have a great career and to deeply, positively impact patients.

Core to our values, we believe there is nothing more important than the health and wellness of you and your family. For benefit eligible employees, we cover 100% of the cost for employee health coverage and offer generous time-off, parental leave, short- and long-term disability, employer paid basic life insurance,  additional voluntary life insurance protection, financial wellness programs including financial planning resources, a 401(k) Plan with an immediately vested employer match, Tuition Reimbursement and Student Loan Repayment, Employee Stock Purchase Plan, commuter subsidy and a variety of wellness offerings to support each person individually.

We are committed to providing a workplace free of discrimination and harassment based on race, color, religion, age, gender, national origin, ancestry, physical or mental or sensory disability (including the use of a trained guide dog or service animal by a person with a disability), genetic information, actual or perceived HIV or Hepatitis C infection, medical condition (cancer or a record or history of cancer and genetic characteristics), marital status, sexual orientation, sexual preference, pregnancy (including childbirth and related medical conditions), disability, veteran status, political ideology, social class (including caste/caste identity), taking or requesting statutorily protected leave, status as a victim of domestic violence, sexual assault or stalking, or any other basis prohibited by applicable law.

To perform this job successfully, you must be able to perform each job responsibility satisfactorily. The job description listed above is representative of the knowledge, skills, and/or abilities required for this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the functions described above.


Sana Biotechnology, Inc. is focused on creating and delivering engineered cells as medicines for patients. We share a vision of repairing and controlling genes, replacing missing or damaged cells, and making our therapies broadly available to patients. We are a team of 320 plus scientists, engineers, clinicians and biotechnology veterans creating an enduring company that makes meaningful medicines and changes how we approach treating disease. Sana has operations in Seattle, Cambridge, and South San Francisco.

Find Us
Sana Biotechnology
188 East Blaine Street, Suite 400
Seattle, WA 98102
United States
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