This job has expired

You will need to login before you can apply for a job.

Senior Principal Scientist, Pathology

Cambridge, MA
Start date
Aug 9, 2022

View more

Science/R&D, Biotechnology, Pathology
Required Education
Position Type
Full time
Genetown, Best Places to Work
You need to sign in or create an account to save a job.

Job Details

Pfizer has an exciting career opportunity available in our Drug Safety Research organization at one of our four locations for a Global Pathologist. Bring your diverse experiences and work with world-class thinkers and leaders with world-class resources within an exceptional, science focused environment.

The Global Pathologist will be a motivated, intellectual partner heavily involved in study design and evaluation in order to develop an understanding of drug mechanisms of action, biomarkers, toxicity, and their relevance to humans to further advance therapies for unmet medical needs. You will be supporting our therapeutic areas: Oncology, Rare Disease, Vaccines, Internal Medicine, and Inflammation and Immunology. The Global Pathologist will be managed and supported by a highly accomplished, board certified pathologist.

Pathologists provide morphologic and mechanistic data interpretation and regulatory or scientific expertise to projects and programs from idea to loss of exclusivity. They also interpret clinical pathology data, other scientific endpoints, and diagnose microscopic and macroscopic changes in tissues from animals in investigative and regulatory studies used to support drug discovery, research and development. Pathologists may use a variety of ancillary aids and instrumentation (EM, IHC, in situ hybridization etc.) and may direct or oversee either regulatory or investigative studies as well as serve on disciplinary or interdisciplinary teams.


  • Perform all regulatory responsibilities in compliance with applicable regulatory standards.
  • Provide Pathology expertise to Drug Safety by evaluating microscope slides, virtual/electronic images and data.
  • Integrate data and present findings and interpretations in written and oral reports to peers, management, and regulatory agencies.
  • Provide input on study design.
  • Provide expert scientific review and oversight of pathology including internal and external peer-review and report review.
  • Provide pathology expertise to teams that may extend from early research to late-stage development.
  • Initiate, run, and/or interpret studies to determine CIR, CIS of targets or compounds and to evaluate models of disease.
  • Lead or provide expertise to issues management teams or mechanistic studies.
  • Establish new assays and technologies for mechanistic studies, biomarkers, and automation. In particular, support the oncology IHC lab locally as well as other investigative techniques.
  • Consult with subject matter experts as necessary.
  • Additional roles include serving as a representative on project teams in the capacity of either a drug development scientist or project team pathologist.


  • D.V.M., V.M.D. degree with advanced education and training in Veterinary Pathology
  • 1-5 Years of Pharmaceutical or relevant experience
  • Demonstrated familiarity with compliance and regulatory standards in a pharmaceutical environment
  • Demonstrated early to late stage pathology experience


  • Formal training and/or certification in Veterinary Pathology (e.g. ACVP, JCVP, MRCPath, ECVP or equivalent);
  • Strong industry experience in Toxicologic and/or Investigative Pathology;
  • An ability to work collaboratively in a matrixed, multi-disciplinary environment.

Other Job Details:

  • Relocation Support Available
  • Locations: Cambridge, MA is highly preferred; La Jolla, CA, Pearl River, NY or Groton, CT
  • Eligible for Employee Referral Bonus
  • #LI-PFE

Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development


Join world-class scientists and leaders who are dedicated to bringing therapies that will significantly improve patients' lives.

As one of the world's premier innovative biopharmaceutical companies, we're driven to discover the cure --driven to significantly improve the lives of everyone...everywhere. If you're similarly driven, you'll find there's no better place to begin --and continue --your career than at Pfizer.

Science is the foundation of our company.  This is why it's no surprise that the most driven scientists in the world choose to carry out their life's passion at Pfizer.  We arm them with the resources, technology, and facilities they need to solve some of the world’s most complex health challenges. This combination empowers our scientists with expertise in vaccines, small-molecule medicines, biotherapeutics amongst many others, to collaborate on breakthrough science, including the world's first mRNA-Based Covid19 vaccine.  Our colleagues advance science and technologies into the therapies that matter most.

Join us and you'll partner with colleagues of diverse backgrounds and abilities who contribute to all aspects of what we do. Great things happen when people come together with one shared goal. If you're driven to discover the cure- ensure it has the latest technology to make it a reality or help improve the lives of others- join those who are similarly driven at Pfizer. The future of medicine is happening here.

Visit and connect with us.



Find Us
(212) 733-2323
235 East 42nd Street
New York, NY 10017
United States
You need to sign in or create an account to save a job.

Get job alerts

Create a job alert and receive personalized job recommendations straight to your inbox.

Create alert