Scientist

Scientist

Job ID: req2763
Employee Type: exempt full-time
Division: Laboratory Animal Science Program
Facility: Frederick: Ft Detrick
Location: PO Box B, Frederick, MD 21702 USA

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc.  The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.

PROGRAM DESCRIPTION     

The Laboratory Animal Sciences Program (LASP) provides exceptional quality animal care and technical support services for animal research performed at the National Cancer Institute at the Frederick National Laboratory for Cancer Research. LASP executes this mission by providing a broad spectrum of state-of-the-art technologies and services that are focused on the design, generation, characterization, and application of genetically engineered and biological animal models of human disease, which are aimed at the development of targeted diagnostics and therapies. LASP contributes to advancing human health, developing new treatments, and improving existing treatments for cancer and other diseases while ensuring safe and humane treatment of animals.

KEY ROLES/RESPONSIBILITIES

• Designing CRISPR-mediated experiments which include, but not limited to, gene knockouts, gene knock-ins, custom targeted libraries
• Interface with the collaborating investigators on projects – providing guidance, consultation, and responding to queries in a timely manner
• Assist the laboratory director in project management and generating activity reports
• Performing CRISPR-mediated experiments in mammalian cells – gene knockouts, clonal cell line generation, and genetic screens
• Illumina-based targeted amplicon sequencing
• Cloning plasmid constructs when needed
• Contributing to manuscripts from both projects led by the GMC as well as supported by the GMC

BASIC QUALIFICATIONS

To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

• Possession of a (CHEA) PhD or an MD (or a combination) degree from an accredited college or university according to the Council for Higher Education Accreditation. Foreign degrees must be evaluated for U.S. equivalency 
• Fundamental understanding and expertise in the CRISPR/Cas9 technology as well as general molecular biology
• Well-developed self-organization, project planning and time management skills
• Expertise in computer-based data acquisition, management, and data analysis
• Ability to plan, conduct, troubleshoot, and optimize scientific experiments
• Extensive communication and presentation skills, ability to prepare comprehensive informative project documentation and other written deliverables, such as manuscripts, meeting abstracts, etc. 
• Prior research accomplishments documented e.g. in the form of significant publications in peer-reviewed journals, meeting poster presentations, invited talks, and other evidences of scientific achievements
• Ability to obtain and maintain a security clearance
  

PREFERRED QUALIFICATIONS

Candidates with these desired skills will be given preferential consideration:

• Software programming and development in python
• Experience running scripts and code on a high-performance computing (HPC) platform

JOB HAZARDS

• This position is subject to working with or have potential for exposure to infectious material, requiring
  medical clearance and immunizations

Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)

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