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Sr. Scientist, Infectious Disease Research

Moderna, Inc.
Cambridge, MA
Start date
Aug 5, 2022

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Job Details

The Role:

Modernas Infectious Disease Research group is seeking a talented, experienced and motivated Computational Immunologist to be part of the vaccine discovery team for a wide range of disease targets. The Senior Scientist will apply expertise in computational biology, statistics, and bioinformatics to probe diverse OMICs datasets to define correlates of immunity and vaccine mechanism of action. The Senior Scientist will work with other members of the Infectious disease team, across disease areas, and with external collaborators on the discovery and development of Modernas mRNA vaccine and immunotherapy candidates and help to advance these into IND-enabling studies. The Senior Scientist will collaborate with other cross-functional teams to evaluate designed mRNAs in the lab and present results internally and externally. The role will involve collaboration with other scientists within the Moderna ecosystem including, among others, cellular immunologists, virologists, bacteriologist and computational scientists to design novel vaccine candidates against infectious disease targets. Located in Cambridge, MA, the Senior Scientist should be outstanding in their fields, collaborative team members and excellent communicators.

Heres What Youll Do:

  • Integrate distinct OMIC datasets

  • Develop novel analytical pipelines to define and validate correlates of immunity

  • Develop antigen-specific receptor analytical pipelines

  • Propose novel vaccine and therapeutic target design approaches inspired by correlates of immunity

  • Interpret, troubleshoot, and report complex data.

  • Align with Infectious Disease Research group members for key antigen design needs and the evaluation of the designed mRNA vaccine candidates.

  • Work closely with cross-functional teams across the Moderna ecosystem, collaborators and CROs to progress candidates from discovery through IND-enabling studies.

  • Maintain expertise in the field of infectious disease, immunotherapy and therapeutic developments, biomarker discovery and patient outcomes, attend conferences, and liaise with external experts in the field.

  • Manage multiple projects and interactions with supporting functions.

  • Apply scientific expertise to accelerate new strategies to exploit mRNA for vaccine and immunotherapy.

  • Provide scientific and technical support to interdisciplinary project teams.

  • Prepare documents and present strategy, results, project updates, and summaries.

Heres What Youll Bring to the Table:

  • Exceptional PhD in Computational Biology, Computer Science, Statistics or related field with minimum three years of postdoctoral experience.

  • Experience in transcriptomic, proteomic, or immune data is required. We are particularly interested in candidates with prior experience in systems serological analysis.

  • Experience in T-cell and B-cell clonal repertoire analysis.

  • Experience in multi-omic analysis is a plus.

  • Proven ability to interpret complex data and present conclusions in a clear and understandable way to a broad audience.

  • Strong written and oral communication skills, comfort with senior management interactions

  • Strong time management and problem-solving skills.

  • Positive team building and teamwork skills, willing to give and receive constructive feedback

  • Proven track record of high impact publications and presentations in the field of protein or antigen design.

  • The Ability to work in a cross-functional work environment is critical, engagement with personnel in different parts of the company; strong leadership skills and independence are expected.

  • Excellent written, presentation and interpersonal communication skills; ability to influence and collaborate in a team environment.

  • Candidate will be curious in exploring new paths for vaccine and drug discovery, bold in proposing creative experimental designs and ideas. Will work collaboratively with multifunctional teams and will be relentless in pursuing successful outcomes.

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

  • Highly competitive and inclusive medical, dental and vision coverage options
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
  • Family care benefits, including subsidized back-up care options and on-demand tutoring
  • Free premium access to fitness, nutrition, and mindfulness classes
  • Exclusive preferred pricing on Peloton fitness equipment
  • Adoption and family-planning benefits
  • Dedicated care coordination support for our LGBTQ+ community
  • Generous paid time off, including:
    Vacation, sick time and holidays
    Volunteer time to participate within your community
    Discretionary winter shut down
    Paid sabbatical after 5 years; every 3 years thereafter
  • Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
  • 401k match and Financial Planning tools
  • Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
  • Complimentary concierge service including home services research, travel booking, and entertainment requests
  • Free parking or subsidized commuter passes
  • Location-specific perks and extras!

Candidates should be aware that Moderna currently maintains a policy requiring all US-based employees to be fully vaccinated against COVID-19 and receive a booster shot once eligible. Newly hired employees must be vaccinated and boosted prior to their employment start date. Moderna is an equal opportunity employer and will provide a reasonable accommodation to those unable to be vaccinated or receive a booster where it is not an undue hardship to the company to do so as provided under federal, state, and local law.

About Moderna

In over 10 years since its inception, Moderna has transformed from a research-stage company advancing programs in the field of messenger RNA (mRNA), to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across seven modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for rapid clinical and commercial production at scale. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna's capabilities have come together to allow the authorized use and approval of one of the earliest and most effective vaccines against the COVID-19 pandemic.

Moderna's mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and autoimmune diseases. Moderna has been named a top biopharmaceutical employer by Science for the past seven years. To learn more, visit

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.




Moderna is advancing messenger RNA (mRNA) science to create a new class of transformative medicines for patients. Moderna’s platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, providing the Company the capability to pursue in parallel a robust pipeline of new development candidates. Moderna is developing therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases and cardiovascular diseases, independently and with strategic collaborators.

mRNA is now a turning point in the history of science, medicine, technology, even humankind itself. With this breakthrough discovery, many of the world’s biggest and most challenging medical problems are no longer a question of “how?” but merely a question of “when?”

Come with us as we pursue the uncharted reaches of possibility and make your mark on the future of medicine.


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