Regeneron Pharmaceutical’s Analytical Chemistry group, located at Tarrytown, NY is seeking a highly motivated and collaborative individual to join our group. The successful candidate will be working in a state-of-the-art mass spectrometry lab and developing analytical methods for Bioanalysis & Therapeutic protein characterization to support R&D pipelines. This will be a lab-based role with focus on hands-on experiments and mass spectrometry data analysis. The candidate will report to a staff scientist and will work in a cross-functional team environment. This role will also be involved in developing innovative mass spectrometry technologies to support Regeneron's upstream R&D programs.
A Typical Day Might Include the Following:
This Role May Be For You If:
Develop primarily LC-MS based methods and conduct analytical experiments on biological samples or therapeutic proteins. Analyze mass spectrometry data to quantify biologics or elucidate critical quality attributes of therapeutic proteins.
Maintain detailed records of experimental protocols. Document experiments, results and findings in electronic laboratory notebook (ELN) in accordance with company policy.
Plan and work independently with minimal supervision; Troubleshoot and fix common analytical methods.
Analyze data and summarize results in a quality form to present at the group and department meetings; Participate in the writing of technical reports, SOPs, and analytical method protocols, etc.
Conduct analytical methods qualification as necessary to support late-stage program developments.
Provide support for regulatory submissions and peer-reviewed publications.
Participate in the general lab maintenance and instrument upkeep.
0-5 years of hands-on laboratory experience
Good understanding of mass spectrometry techniques and their applications to protein/peptide analysis, as well as other protein analysis techniques
Previous hands-on experience with chromatographic separation, sample processing, quantitative/qualitative assays
Attention to detail, good record keeping and organizational skills
Ability to think and act creatively and independently, work collaboratively in a team environment.
To be considered for this opportunity, you must have a minimum of a BS degree 0-5 years of a MS degree and 0-2 years' of hands on direct laboratory experience for an Associate level. To be considered for a Specialist, must have a BS degree 5-10 years experience, or a MS +5 years experience. Leveling will be determined through interview process.
Direct experience with liquid chromatography mass spectrometry (LC-MS) related assays for protein analysis and data interpretation skills. Experience with ligand binding assays (e.g. ELISA, MSD) is a plus.
Familiar with advanced mass spectrometry instruments like Q-TOF, Orbitrap, Q-Exactive, Triple Quadrupole, etc...
Experience with analytical methods development and validation/qualification
Experience in the CRO/biotech/biopharmaceutical industry
Bioanalysis and GxP compliance environment experience is a plus.
Good multi-tasking, time management and project handling skills are desired.
Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels!
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.