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Research Associate II

Employer
Sangamo Therapeutics, Inc.
Location
Richmond, CA
Start date
Aug 4, 2022

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Discipline
Regulatory, Research/Documentation, Science/R&D, Research
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Bay
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Job Details

Manager: Scientist III

Department: Design & Technology
Location: Richmond

Sangamo Therapeutics is a genomic medicine company building value with cutting-edge work across four distinct but complementary technology platforms – gene therapy, cell therapy, in vivo genome editing, and in vivo genome regulation. Using its deep scientific expertise and proprietary zinc finger genome engineering technology, Sangamo is working to create genomic cures for patients suffering from severe genetic diseases for which today’s medicines can only treat symptoms. At Sangamo, we are passionate about transforming lives by building a robust, sustainable, differentiated, innovative, and high value genomic medicine pipeline that addresses patients with life-limiting conditions. Sangamo takes pride in being the first to edit endogenous human genes, first to treat patients with gene edited T cells, and first to treat patients with in vivo genome editing. Our top priority is to meet the needs of patients with commitment and compassion. Along with our commitment to science and to our patients, we also endeavor to create an inclusive environment that promotes and values diversity. Sangamo is a company where individuals can flourish, grow and develop their expertise.
 
We are seeking top talent to join our mission. Let’s build a better future together.

JOB SUMMARY:   
Sangamo Therapeutics is seeking a talented Research Associate to join the Zinc Finger platform development team and help us usher in the next generation of genomic medicines. In this role, the candidate will be responsible for the cloning, expression, purification, and characterization of our proprietary Zinc Finger proteins using cutting edge scientific instrumentation. The ideal candidate will have a strong molecular biology background and have a working knowledge of protein science and biophysical methods to characterize protein-DNA interactions. The position requires the ability to work independently as well as in a team environment. The work has a deep impact on the company’s pioneering Zinc Finger technology.


ESSENTIAL FUNCTIONS: 
 

  • Develop, optimize, and execute protocols for the high throughput purification of recombinant proteins expressed in E. coli
  • Biophysical characterization of protein-DNA interactions and analysis of the resulting data
  • Quantification of protein concentration (Absorbance, fluorescence, NanoOrange, Bradford assays)
  • High throughput cloning of protein coding sequences into established expression vectors


 

EDUCATION, EXPERIENCE AND SKILLS REQUIREMENTS:

  • BS or higher in Molecular Biology, Biochemistry, or related field
  • 2+ years of experience in an academic research laboratory or biotechnology company.  Level will be determined by education, experience and skills. 
  • Hands on expertise in molecular cloning
  • Hands on expertise in the following techniques: PCR, SDS-PAGE, sequencing
  • Skilled ability in the documentation, organization and presentation of experimental results
  • Ability to follow and optimize laboratory protocols

Preferred but not required

  • Experience with protein purification methods (Batch, Gravity flow, FPLC)
  • Experience with protein binding assays (Surface plasmon resonance, biolayer interferometry, ELISA)
  • Experience with data fitting and data analysis software
  • Experience using specialized scientific instrumentation
  • Ability to program in Python or R

 
Sangamo is an equal opportunity employer
Sangamo is committed to fostering belonging for all employees and embraces diversity, equity, and inclusion in recruiting and hiring.  All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual’s race, color, sex, gender identity, gender expression, religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws

Commitment to Safety
Sangamo requires all U.S. workers to be fully vaccinated against COVID-19 as of their start date.  This requirement is a condition of employment at Sangamo, and it applies regardless of location or classification of role.  If you are unable to receive the vaccine & booster, you will have an opportunity to request a reasonable accommodation consistent with applicable laws. 

Note to External Recruiters: We do not accept unsolicited resumes from any source other than from the candidates themselves.

Company

Sangamo Therapeutics is a genomic medicine company building value with cutting-edge work across four distinct but complementary technology platforms – gene therapy, cell therapy, in vivo genome editing, and in vivo genome regulation. At Sangamo, we are passionate in developing genomic medicines to transform the lives of patients with serious diseases. We transform lives by building a robust, sustainable, differentiated, innovative, and high value genomic medicine pipeline that addresses patients with life-limiting conditions. Sangamo takes pride in being the first to edit endogenous human genes, first to treat patients with gene edited T cells, and first to treat patients with in vivo genome editing. Our top priority is to meet the needs of patients with commitment and compassion. Along with our commitment to science and to our patients, we also endeavor to create an inclusive environment that promotes and values diversity. Sangamo is a company where individuals can flourish, grow and develop their expertise.

We are seeking top talent to join our mission. Let’s build a better future together.

Stock Symbol: SGMO

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Find Us
Website
Phone
(510) 970-6000
Location
7000 Marina Blvd
Brisbane
CA
94005
United States
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