The Molecular Profiling and Data Science Department is looking for an enthusiastic and motivated Computational Scientist who values independent research in an open and collaborative working environment. You will participate in original studies that span from basic research to translation studies, directly impacting the lives of patients. You will also have the opportunity to develop novel computational methods from internal and external big data resources. You will join a diverse and inspiring team which cultivates discussion across scientists of differing backgrounds at the exciting intersection of function genomics, gene therapy, machine learning, and neuroscience. We work closely with biological researchers from different scientific functions, especially the departments of Neuroscience, Aging, VelociGene and Precision Medicine, to address critical scientific questions.
In this role, a typical day might include the following:
Lead computational efforts in neuroscience by developing or applying innovative methods from single cell genomics, epigenomics, spatial transcriptomics and other sequencing technologies.
Discuss and analyze molecular profiling data generated from gene interference strategies such as CRISPR-Cas9 for target discovery and therapy development
Develop computational methodologies to integrate multiple data modalities to gain new biology insights
Work in concert with pre-clinical and clinical teams to design next-generation sequencing and digital phenotyping experiments, draft data analysis plans, and provide critical analytics support.
Prepare presentations and documentations for collaborators and senior management.
Publish and present novel findings in peer-reviewed journals and conferences.
Contribute to our team efforts in formulating analytical pipelines and benchmarked standards.
This job might be for you if:
You are passionate about understanding and applying efficient computational techniques to address biological questions.
Bring innovative thinking to multi-omics data analysis.
Have a strong work ethic and are proactive in providing solutions to foster scientific collaborations and drive projects forward within Regeneron.
Can effectively communicate with collaborators with various backgrounds.
Value teamwork and team excellence.
To be considered for this role, you must have a PhD degree in Bioinformatics, Biomedical Engineering, Biophysics, Computational Biology, Chemical Engineering, Computer Science, or related quantitative field. Experience with conducting bioinformatics analysis (e.g. bulk and single cell RNA-Seq, ATAC-Seq, spatial transcriptomics, alternative splicing, genomic variation). Strong background (2+ years preferred) in at least in one of the following scripting languages: R, Python, MATLAB. Experience working with single cell analysis tools such as Seurat, Scanpy, etc. Experience working with clinical samples is a plus. Familiarity in working in a Linux environment, shell scripting and Jupyter Notebook environment. Experience with public transcriptomics database such as Human Cell Atlas, Allen Brain Atlas, and GTEx is preferable. Experience with cloud-based big-data analytics and machine learning to integrate omics data with other modalities such as images and sensor readouts is highly valued.
Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels!
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.