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Process Development Associate II, Gene Therapy Purification Development

Employer
Regeneron Pharmaceuticals, Inc.
Location
Tarrytown, New York
Start date
Aug 2, 2022

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Job Details

Regeneron’s Viral Production Core in our Preclinical Manufacturing & Process Development (PMPD) group is looking for a Process Development Associate II focusing on gene therapy purification process development. In this role you will work as part of a multi-functional team to generate Adeno-Associated Virus (AAV) manufacturing processes and products with the aim of providing treatment to unmet medical needs through gene therapy. This is a growth opportunity that combines the excitement and opportunity of a start-up with the security and institutional knowledge gained from working for an established biopharmaceutical company.

A Typical Day in the Role Might Look Like:

  • Support downstream viral vector process development and production through design, characterization, and implementation of robust purification processes suitable for future GMP clinical production.

  • Optimize parameters for purification of AAV-derived viral vectors using multivariate design of experiment approaches.

  • Document experiments, results, and findings in electronic laboratory notebook and LIMS; present work at group and department meetings. Maintain equipment and solve instrumental/experimental problems.

  • Develop expertise in theory and practice of manufacturing steps and analytical methods.

  • Cross-train on and provide support for analytical and upstream operations.  

  • Support weekend or off-hour experimental and pilot scale work, as the need arises.

This Role Might Be for You If:
  • You have strong initiative to complete ambitious tasks and learn new technologies.

  • You are capable of multi-tasking, thinking critically, working both independently and within a team environment.

  • You have excellent interpersonal, verbal and written communication skills.

#LI-Onsite


This position requires a Bachelor’s and/or Master’s degree in either Chemical Engineering, Biochemical Engineering, Biochemistry, or related field with 0-3 years meaningful experience. The extent of the candidate’s prior experience will determine the grade of the position. A strong fundamental understanding of the principles of purification process development and a history of developing downstream steps within bioprocesses is a plus. Experience preferred with some of the following systems : Depth filtration, Tangential flow filtration, Affinity Capture chromatography, Polishing chromatography. Prior experience with producing AAV-based gene therapies is a plus. This job will periodically require short duration physical exertions, including light-medium lifting.

Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.

Company

Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for 30 years by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to seven FDA-approved treatments and numerous product candidates in development, all of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye disease, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, infectious diseases, pain and rare diseases.
 
Regeneron is accelerating and improving the traditional drug development process through our proprietary VelociSuite® technologies, such as VelocImmune® which produces optimized fully-human antibodies, and ambitious research initiatives such as the Regeneron Genetics Center, which is conducting one of the largest genetics sequencing efforts in the world.

Stock Symbol: REGN

Stock Exchange: NASDAQ

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Find Us
Website
Phone
914-847-7000
Location
Corporate Headquarters
777 Old Saw Mill River Road
Tarrytown
New York
10591
United States
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