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Principal Engineer

CSL Behring
Holly Springs, North Carolina
Start date
Jul 29, 2022
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Job Details

Job Description

The Opportunity

Principal Scientist will be a member of Technical Development at the Holly Springs Influenza Vaccine manufacturing facility, supporting Viral Pilot Plant (VPP) operations. You will oversee upstream Cell Culture operations within the VPP. You will independently provide the technical and operation skill-sets necessary to manufacture high quality biological and to meet safety in a compliant, efficient, and cost-effective manner at Seqirus Holly Spring.

You will have responsibilities including providing technical expertise related to the process, equipment, and business systems that inspire manufacturing and strategic improvements within purification processes.

The Role
  • You will be
  • Accountable for personal contribution and VPP upstream team contribution to on upstream purification projects of varying size and complexity.
  • Direct the work of scientific staff on VPP Upstream Cell culture projects.
  • Be an important team member by concurrently advancing multiple prioritized strains using established work processes.
  • Discover work process improvements to achieve future team goals.
  • Prepare technology development study protocols and reports, BPRs, and SOPs to support Viral Pilot Plant
  • Demonstrate awareness of broader project goals; Provide technical guidance to VPP upstream and colleagues in FCC Late Stage group.
  • Analyze information and standard practices using existing procedures to solve routine problems Functional/Technical Skill: Requires in-depth conceptual and practical expertise in own technical or scientific discipline and understand technical terminology relevant to the field. Apply broad theoretical job knowledge typically obtained through advanced education or previous work experience.

Use electronic business systems (e.g, PLCs, LIMS, SAP).

Your skills and experience
  • Postgraduate degree (preferably PhD) or experience in relevant industry or academic environment
  • Minimum 5 years of experience
  • Knowledge of / experience in cell culture
  • Knowledge of bioprocess unit operations (e.g. Bioreactors, centrifugation,) and engineering scaling principles is required
  • Experience in application / analysis of Design of Experiments (DOE) and other statistical techniques
  • Knowledge of GMPs.
  • Benefits: Medical, Dental, Vision, Life Insurance, 401K, and PTO available from your first day of hire.

About Us

Our Benefits

Seqirus is committed to attracting and retaining world-class employees who are valued for their contributions to achieving business objectives. Learn more about some of the benefits you can participate in when you join Seqirus.

About Seqirus

Seqirus is part of CSL Limited (ASX: CSL). As one of the largest influenza vaccine providers in the world, Seqirus is a major contributor to the prevention of influenza globally and a transcontinental partner in pandemic preparedness. Learn more about Seqirus.

We want Seqirus to reflect the world around us

As a global organisation with employees in 35+ countries, CSL embraces diversity, equity and inclusion. Learn more about Diversity, Equity & Inclusion at Seqirus.

Do work that matters at Seqirus!


As the third largest global biotechnology company with employees in more than 35 countries, CSL Behring is focused on serving patients with serious and rare diseases, including coagulation disorders, primary immune deficiencies, hereditary angioedema, respiratory disease and neurological disorders. We collaborate with patient and biomedical communities to improve access to therapies, advance scientific knowledge and support future medical research. 

CSL Behring's dynamic environment fosters innovation and attracts the best and brightest who share a commitment to helping save lives. People here are free to live their Promising FUTURES where they can fulfill their individual career aspirations and realize their potential. 

CSL Behring is committed to diversity and inclusion, both of which underpin our Values of patient focus, innovation, collaboration, integrity and superior performance. We believe that by harnessing and honoring the unique capabilities, experiences and perspectives of our people, we are better able to serve our patients.

CSL Behring operates one of the world's largest plasma collection networks, CSL Plasma. The parent company, CSL Limited, headquartered in Melbourne, Australia, employs more than 27,000 people, and provides its life-saving medicines in more than 70 countries. 
For more information visit Help us deliver on our promise to save lives and protect the health of people around the world. Promising FUTURES start at CSL Behring!

Stock Symbol: CSL

Stock Exchange: Australian Securities Exchange

Find Us
1020 First Avenue
King of Prussia
United States
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