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Scientist, Clinical Biomarker Laboratory, Flow Cytometry

Moderna, Inc.
Norwood, MA
Start date
Jul 29, 2022

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Job Details

The Role:

Moderna is seeking a talented, experienced, and motivated Scientist to join the Clinical Flow Cytometry group to serve as a scientific expert for flow cytometry assay development, qualification/validation to support clinical programs across multiple therapeutic areas. The Scientist will work with a team of scientists and will be responsible for the design and execution of high parameter spectral flow cytometry assay development, qualification/validation, and the running of clinical samples to deliver high quality, key data for clinical trials conducted by Moderna. The candidate will have broad knowledge of best practices in flow cytometry, experience with spectral cytometry, and a proven record of building robust assays. The Scientist will effectively communicate across multi-disciplinary teams to contextualize program needs and effectively plan studies to meet data rigor expectations and deliver data within required timelines. In addition, the candidate will be involved in the training of junior team members when and where needed to perform analytical work and maintain clinical testing continuity.

Here's What Youll Do:

  • Work with a team of scientists to develop high parameter spectral flow cytometry assays and apply them to clinical trial samples to generate key data for clinical decision making.

  • Plan, organize, and execute assay qualification and fit-for-purpose validation studies

  • Run experiments independently and accurately analyze and present data

  • Conduct ex vivo experimental work for functional profiling of immune system

  • Serve as a lead in the execution of multiple projects requiring flow cytometry expertise

  • Formulate novel solutions, using multiple approaches, including ex vivo assays for the design of complex experiments

  • Research scientific and technical literature to propose and implement new flow assays and/or innovative solutions applicable to the laboratory

  • Work with the team to establish documentation procedures and workflows aligned to clinical cytometry industry expectations and regulations

  • Identify and resolve quality issues, employ mitigation strategies, and escalate issues

  • Identify and work to alleviate bottlenecks in current workflows to increase efficiency

  • Educate and train junior staff in flow cytometry, technical detailed execution of assays, and documentation requirements and workflows where appropriate.

Heres What Youll Bring to the Table:

  • Ph.D. or MS with 3+ years of high parameter flow cytometry experience

  • In depth experience running and maintaining flow cytometers such as Cytek Aurora, BD Fortessa/Symphony, etc.

  • Understanding and experience in Spectral flow cytometry

  • In depth experience in establishing complex multiparameter flow cytometry assays including immunophenotyping and ex vivo cell-based assays for functional profiling such as intracellular cytokine staining, cell activation and proliferation, etc.

  • Strong level of understanding and expertise in design and executing immune-related studies and assays

  • Experience with flow cytometry assay fit-for-purpose validation applicable for intended use of data

  • The ability to work in a cross-functional work environment with effective communication skills to contextualize program needs and effectively plan studies to meet data rigor expectations and deliver data within required timelines

  • Excellent organizational and planning (project management) skills

  • Flexibility with changing priorities and urgent project requests

  • Established record to effectively educate and train junior staff

  • Experience in high parameter data analysis using software such as FCS Express, Flowjo, OMIQ

  • Possess strong computational skills in Excel, Power Point, Word, and GraphPad Prism

  • Excellent documentation practices

  • Experience in clinical lab setting is desired

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

  • Highly competitive and inclusive medical, dental and vision coverage options
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
  • Family care benefits, including subsidized back-up care options and on-demand tutoring
  • Free premium access to fitness, nutrition, and mindfulness classes
  • Exclusive preferred pricing on Peloton fitness equipment
  • Adoption and family-planning benefits
  • Dedicated care coordination support for our LGBTQ+ community
  • Generous paid time off, including:
    Vacation, sick time and holidays
    Volunteer time to participate within your community
    Discretionary winter shut down
    Paid sabbatical after 5 years; every 3 years thereafter
  • Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
  • 401k match and Financial Planning tools
  • Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
  • Complimentary concierge service including home services research, travel booking, and entertainment requests
  • Free parking or subsidized commuter passes
  • Location-specific perks and extras!

Candidates should be aware that Moderna currently maintains a policy requiring all US-based employees to be fully vaccinated against COVID-19 and receive a booster shot once eligible. Newly hired employees must be vaccinated and boosted prior to their employment start date. Moderna is an equal opportunity employer and will provide a reasonable accommodation to those unable to be vaccinated or receive a booster where it is not an undue hardship to the company to do so as provided under federal, state, and local law.

About Moderna

In over 10 years since its inception, Moderna has transformed from a research-stage company advancing programs in the field of messenger RNA (mRNA), to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across seven modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for rapid clinical and commercial production at scale. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna's capabilities have come together to allow the authorized use and approval of one of the earliest and most effective vaccines against the COVID-19 pandemic.

Moderna's mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and autoimmune diseases. Moderna has been named a top biopharmaceutical employer by Science for the past seven years. To learn more, visit

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.




Moderna is advancing messenger RNA (mRNA) science to create a new class of transformative medicines for patients. Moderna’s platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, providing the Company the capability to pursue in parallel a robust pipeline of new development candidates. Moderna is developing therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases and cardiovascular diseases, independently and with strategic collaborators.

mRNA is now a turning point in the history of science, medicine, technology, even humankind itself. With this breakthrough discovery, many of the world’s biggest and most challenging medical problems are no longer a question of “how?” but merely a question of “when?”

Come with us as we pursue the uncharted reaches of possibility and make your mark on the future of medicine.


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