Sr. Research Associate/Scientist (1 yr contract)

Scorpion Therapeutics is a precision oncology company founded in February 2020 by a preeminent group of scientists from Harvard University/Massachusetts General Hospital – Keith Flaherty, MD, Gaddy Getz, Ph.D. and Liron Bar-Peled, Ph.D. The company has raised $270M in Series A and Series B financings led by blue-chip investors, including Atlas Venture, Boxer Capital of Tavistock Group, EcoR1 Capital, LLC, Omega Funds, and Vida Venture.

Scorpion Therapeutics’ mission is to serve oncology patients by discovering and developing best-in-class and first-in-class, small molecule cancer medicines that address large patient segments with significant unmet medical needs. To accomplish this mission, we are building a highly collaborative team focused on the pursuit of novel approaches to small molecule drug discovery. This approach relies upon dynamic collaboration between cancer biology, proteomics, informatics, structural biology and medicinal chemistry – with the ultimate goal of realizing the full potential of targeted/precision oncology.

We are seeking a highly motivated research associate to join our dynamic transcription factor biology drug discovery team in Boston.  This candidate will serve a critical role in establishing and running cell-based assays to inform transcription factor biology and mechanism of action, as well as help drive our small molecule drug discovery programs targeting transcription factors. This one-year contract position is ideal for a talented, highly motivated and results driven individual seeking valuable industry experience working in a fast-paced, innovative, start-up environment.

KEY RESPONSIBILITIES

• Engineering high-quality assay-ready cell lines to support several pipeline projects.
• Developing and executing cell-based assays and downstream mechanism of action studies with genetically manipulated cells and/or small molecule inhibitors.
• Developing pharmacodynamic readouts to inform drug development efforts.
• Presenting data and key findings at cross-functional team meetings

PROFESSIONAL EXPERIENCE/QUALIFICATIONS

• BS/MS in Biology or a related field, ideally with 2+ years of experience.
• Strong proficiency in mammalian cell culture.
• Prior experience in cell line engineering, specifically working with lentiviral vectors.
• Prior experience in at least one of the following: CRISPR/RNAi based perturbations; transcription factor reporter assays/EMSA; RNA-seq sample preparation/analysis; qPCR
• Driven multitasker with a strong attention to detail and organizational skills
• Desire to work in a fast-paced, multi-tasking environment, while employing tact, patience, diplomacy and a collaborative spirit.
• Exceptional interpersonal and communication skills.

Scorpion Therapeutics Inc. is an Equal Opportunity Employer who strives to create and maintain a diverse working environment. We do not discriminate for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Beginning October 13, 2021, Scorpion Therapeutics requires all new hires to be fully vaccinated against COVID-19. If you are unable to receive the vaccine due to a disability or serious medical condition, or because of your sincerely held religious beliefs, you will have an opportunity to request a reasonable accommodation.