Research Associate II, Analytical Development, Cell Therapy

Resilience is seeking a talented Research Associate 2 to join the Cell Therapy Analytical Development team. This team is responsible for the design, development, and implementation of assays to advance the company’s novel T cell therapy programs. This researcher should have a background in assay development, preferably in molecular and cellular immunology and immune-oncology, while also possessing strong interpersonal skills and the ability to work collaboratively with other groups within the organization.

Job Responsibilities

• Perform sample testing of lentiviral vector and T cell products using protein, cellular and molecular assays to determine the activity of drug substance and drug product and respective process contaminants

• Assist in development, optimization and troubleshooting of new methods to improve capabilities and throughput in the analytical development laboratory

• Assist in the technology transfer of analytical methods to other departments and support analytical method qualification and/or validation if needed

• Assist in routine maintenance and calibration of analytical equipment

• Prepare technical documents including SOPs, method protocols and reports

• Assist in compiling data for review and discussion within the Cell Therapy team

• Utilize digital technology (LIMS/ELN) for recording lab activities

Required Qualifications

• Bachelor’s or Master’s degree in cell biology, immunology, molecular biology, virology, pharmaceutical sciences, or a closely related field; with 1-3 years of experience in an industry setting

• Experience using mammalian cell culture techniques and common immunological methods (ELISA, cytokine assays, flow cytometry, etc.)

• Good organizational skills and the ability to multitask

• A self-starter and team player who can balance the velocity of startup environment with the quality and rigor of a clinical regulatory environment

Preferred Qualifications

• Prior experience in RNA/DNA isolation and molecular biology assays (qPCR, ddPCR, qRT-PCR) and related analytical software

• Experience with analytical or statistical software, e.g., Flowjo, Softmax Pro, GraphPad Prism

• Working knowledge of cGMP Quality systems