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Head of Immunology Research

Employer
AnaptysBio, Inc.
Location
San Diego, CA
Start date
Jul 21, 2022

View more

Discipline
Regulatory, Science/R&D, Research, Immunology
Required Education
Doctorate/PHD/MD
Position Type
Full time
Hotbed
Biotech Beach
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Job Details

Job Type Full-time

Position Summary

This position will be responsible for overseeing and directing the activities of a team of scientists in the implementation and execution of antibody-based drug discovery projects in immunology. The individual will lead cross-functional drug discovery projects, manage and direct cell biology associates and scientist-level personnel across programs, collaborating with others in research and development in alignment with company objectives. The individual will be involved in regular program reviews, new target proposal reviews, and help maintain high standards of scientific excellence. Major responsibilities will include implementing antibody discovery, cell-based strategies for antibody screening, and antibody optimization.

Essential Functions

  •  Directs the activities of an immunology team of scientists in the discovery and optimization of therapeutic antibodies.
  •  Develops and successfully coordinates strategies to ensure effective achievement of project and company goals.
  •  Provides immunology support to multidisciplinary project teams and participates in strategies for generating clinical candidates.
  •  Initiates projects and/or leads therapeutic antibody discovery project teams, including designing key strategies and interpreting results to further project objectives, working effectively across disciplines to accomplish project goals.
  •  Ensures scientific excellence within cell biology and across research programs.
  •  Regularly reviews and interprets research data, monitors and evaluates scientific progress.
  •  Maintains broad scientific and technical knowledge within disciplines relevant to AnaptysBio’s drug discovery projects and in-depth knowledge relevant to specific drug discovery projects.
  •  Presents research findings and conclusions clearly and effectively to senior management, scientific advisory panels, and at external meetings, as appropriate.

Supervisory Responsibilities

  •  Hire, lead, and develop Team of 10 - 15.
Requirements

Education & Experience: 

  • PhD plus 12 years post-doctoral experience in Immunology, Cell Biology, Biomedical Sciences, or a related field with 8 years productive experience in the biotechnology or pharmaceutical industry in biologics drug discovery.
  • Demonstrated success in project leadership, independent and innovative scientific thinking and experimental design/approaches.
  • At least five years’ experience managing and leading a group of biologists in a matrixed project team environment.
  • Strong scientific publication and external presentation record in accord with years of experience.
  • Experience working on a project that has transitioned into clinical development successfully.

Knowledge Requirements: 

  • Strong working knowledge of cellular and molecular immunology, including autoimmune and inflammatory diseases, with an applied understanding of antibodies, antibody generation and characterization, and biologics drug discovery research.
  • Demonstrated success in drug discovery project leadership, independent and innovative scientific thinking and experimental design/approaches.
  • Knowledgeable in flow cytometry approaches.

Physical Demands

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

While performing the duties of this job, the employee is regularly required to sit and talk or hear. The employee frequently is required to use hands to finger, handle, or feel. The employee is occasionally required to stand, walk, and reach with hands and arms. The employee must occasionally lift and/or move up to 10 pounds. Specific vision abilities required by this job include close vision and ability to adjust focus in order to read.

Work Environment

The work environment characteristics are representative of those an employee encounters while performing the essential functions of this job, typically in an open office environment. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

The noise level in the work environment is usually moderate.

May be required to travel by plane or car.

This position requires working with biological and/or chemical hazards

 All qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or other legally protected status.  

Company

AnaptysBio is a clinical-stage antibody development company advancing therapeutic antibody product candidates focused on unmet medical needs in inflammation. We develop our product candidates to address emerging biological targets using our proprietary antibody discovery technology platform, which is based upon a breakthrough understanding of the natural process of antibody generation, known as somatic hypermutation, or SHM, and replicates this natural process of antibody generation in vitro. Our strategy is to advance the development and commercialization of our proprietary product candidates, and for certain programs, establish partnerships with leading biopharmaceutical companies where we retain certain development and commercialization rights in the United States.
Our wholly-owned product pipeline includes etokimab (ANB020) and ANB019, which are being developed to treat severe inflammatory disorders with unmet medical need. We are advancing etokimab, our proprietary anti-interleukin-33 antibody, for the treatment of atopic dermatitis, eosinophilic asthma and chronic rhinosinusitis with nasal polyps.
In addition, we are developing our ANB019 product candidate, an antibody that inhibits the interleukin-36 receptor, for the treatment of rare inflammatory diseases called generalized pustular psoriasis (GPP) and palmoplantar pustulosis (PPP).
Our company is led by a strong management team with a proven track record of successfully growing biotechnology companies with deep experience in antibody discovery and development, collaborations, operations and corporate finance.
Additionally, multiple AnaptysBio-generated antibodies have entered the clinic under our immuno-oncology-focused collaboration with TESARO and inflammation-focused collaboration with Celgene.

Stock Exchange: NASDAQ

Stock Symbol: ANAB

Find Us
Website
Phone
858-362-6295
Location
10421 Pacific Center Court
Suite 200
San Diego
California
92121
United States
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