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(Lead) IT Engineer

Vaxcyte, Inc.
San Carlos, California
Start date
Jul 21, 2022

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Information Technology, General
Required Education
Bachelors Degree
Position Type
Full time
Biotech Bay
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Job Details

Company Profile:

Vaxcyte, Inc. (Nasdaq: PCVX) is a vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases. The Company is developing broad-spectrum conjugate and novel protein vaccines to prevent or treat bacterial infectious diseases. Vaxcyte’s lead candidate, VAX-24, is a 24-valent, broad-spectrum pneumococcal conjugate vaccine being developed for the prevention of invasive pneumococcal disease (IPD). The Company is re-engineering the way highly complex immunizations are made through modern synthetic techniques, including advanced chemistry and our exclusively licensed XpressCFTM cell-free protein synthesis platform. Unlike conventional cell-based approaches, the Company’s system for producing difficult-to-make proteins and antigens is intended to accelerate its ability to efficiently create and deliver high-fidelity vaccines with enhanced immunological benefits. Vaxcyte’s pipeline also includes VAX-XP, a PCV with an expanded breadth of coverage of greater than 30 strains; VAX-A1, a prophylactic vaccine candidate designed to prevent Group A Strep infections; and VAX-PG, a therapeutic vaccine candidate designed to slow or stop the progression of periodontal disease. The Company is driven to eradicate or treat invasive bacterial infections, which have serious and costly health consequences when left unchecked. For more information, visit
Vaxcyte, headquartered in San Carlos, CA, went public in June 2020 and currently has a team of approximately 100 employees and anticipates continued, significant growth. On January 6, 2022, Vaxcyte announced that the U.S. Food and Drug Administration (FDA) had cleared the Investigational New Drug (IND) application for VAX-24, its lead vaccine candidate. The Company expects to initiate the VAX-24 Phase 1/2 clinical proof-of-concept study in adults in the first quarter of 2022 and announce Phase 2 topline immunogenicity, safety and tolerability results by the end of the year. VAX-24 was designed to prevent IPD, which can be most serious for infants, young children, older adults and those with immune deficiencies or certain chronic health conditions. Given the global impact of pneumococcal disease remains significant, the public health community continues to advocate for vaccines that can offer broader protection to prevent IPD. Vaxcyte’s PCV franchise, consisting of VAX-24 and VAX-XP, is designed specifically to address this need and has the potential to deliver the broadest protection for this very serious disease.
Essential Functions:
    • Provide outstanding end-user technical support by practicing excellent communication and customer service.
    • Possess strong problem-solving skills with the ability to listen to the user’s concerns, identify problems and develop a plan for resolution.
    • Plan, organize, schedule, and supervise the day-to-day technical support activities, including troubleshooting, customer service issues, approvals, and installations.
    • Leading teams of IT specialists with ticket triage and operational excellence.
    • Measure, monitor, and maintain team’s ability to meet or exceed contact and resolution Service Level Agreements (SLA).
    • Own monitoring and maintenance for critical IT infrastructure, including equipment, access, license management, upgrades, patch management, and troubleshooting.
    • Create and maintain asset management for hardware and software.
    • Assist in the development and maintenance of policies, procedures, and processes.
    • Oversee protocols and procedures for all software applications and hardware.
    • Proactively applies professional concepts to contribute to development of company's concepts and principles and to achieve objectives in creative and effective way.
    • Plan, justify, and bring to closure information technology projects.
    • Setup and administration of SaaS-based solutions for the enterprise.
    • Work with internal and external stakeholders to upgrade SaaS software as needed.
    • Monitoring the roll-out of new software applications to ensure the smooth transition.
    • Provide administrator-level hands-on-keyboard support for all referenced technology platforms.
    • Document all processes and create user training manuals / knowledge base.
    • Develop, test and deploy images and application packages.
    • Scale our endpoint management tools, network and AV infrastructure, on-boarding and off-boarding procedures, helpdesk request handling, identity and access management, and overall IT processes.
    • Maintain security patching for supported desktop applications and operating systems.
    • Own build-outs and IT needs for our new headquarters and Lab space.
    • Keep current with the latest technologies and determine what new technology solutions and implementations will meet business demand.
    • You should expect the role and responsibilities to develop and evolve as the project group expands.

    • Bachelor’s Degree in Information Systems or related field is a plus.
    • 4yrs + years of IT Operations experience .
    • You’re a self-starter who can prioritize and work autonomously based on common goals and objectives with little direct supervision and as a part of a team.
    • You don’t ask for permission; you understand the downstream effects of your actions while following policies and procedures.
    • You are capable working with cross functional teams, ability to understand technical requirements when working with non-technical teams and translate the project into a clear story that keeps everyone aligned.
    • Proven analytical and problem-solving abilities.
    • Strong leadership, communication, and customer service skills.
    • Knowledge of ticketing system management (Confluence, Slack, FeshDesk).
    • A deep understanding of Identity and Asset management concepts.
    • Strong knowledge of enterprise applications, tools and operating systems, including Windows, Mac OS, Office 365, Azure Active Directory, Intune/Autopilot, Okta SSO/MFA, Cisco Meraki firewall, switches, AP’s.
    • Working knowledge of SaaS system administration.
    • You are passionate about resolving root causes for issues.
    • Experience working with API’s and have a natural drive for automation and simplification.
    • Automation and Programing experience is a plus.
    • Proficiency in one or more scripting languages.
    • Ability to handle stressful situations.
    • High sense of responsibility.
    • Ability to adhere to all company policies, safety regulations and procedures.
    • Maintain confidential information.
    • Experience utilizing remote access tools to troubleshoot.
    • The ability to remain current with new software developments.
    • Ability to learn new technologies quickly.
    • Experience and knowledge of ITIL governance and practices.
    • Understands and applies best practices with managing data ie. file shares, backup/recovery and disaster recovery.
    • Good understanding of cybersecurity and policies.
    • Knowledge of audiovisual systems and basic AV troubleshooting.
    • All Vaxcyte employees require vaccination against COVID-19.

Reports to: Sr. Manager, IT

Location: San Carlos, CA
The compensation package will be competitive and includes comprehensive benefits and an equity component.


Vaxcyte, Inc. (Nasdaq: PCVX) is a next-generation vaccine company seeking to improve global health by developing superior and novel vaccines designed to prevent some of the most common and deadly infectious diseases worldwide. Our exclusively licensed cell-free protein synthesis platform and our proprietary know how enable us to design and produce optimized protein carriers and antigens, the critical building blocks of vaccines, in ways that we believe conventional vaccine technologies cannot. Our lead vaccine candidate, VAX-24, is a preclinical, 24-valent broad-spectrum pneumococcal conjugate vaccine (PCV) being developed for the prevention of invasive pneumococcal disease. Our pipeline also includes VAX-XP, a PCV with an expanded breadth of coverage of at least 30 strains; VAX-A1, a prophylactic vaccine candidate designed to prevent Group A Strep infections; and VAX-PG, a therapeutic vaccine candidate designed to slow or stop the progression of periodontal disease by targeting the keystone pathogen responsible for this chronic, oral inflammatory disease.

Find Us
(650) 837-0111
353 Hatch Drive
Foster City, CA 94404
United States
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