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Senior Manager/Associate Director, Diagnostic Bioinformatics

Employer
Mammoth Biosciences
Location
Brisbane, CA
Start date
Jul 6, 2022

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Job Details

OPPORTUNITY
Mammoth is seeking an Senior Manager / Associate Director with expertise in bioinformatics and software engineering to join its Diagnostics team. This role will lead a team focused on designing new diagnostics assays, supporting data needs for on-going research projects, and developing in-house software tools for data analysis and data tracking.

The successful candidate will contribute towards Mammoth’s efforts to develop innovative CRISPR-based diagnostic products that enable consumers to access their health information in a timely manner. This position will work closely with both the diagnostics research and development teams on a variety of projects including primer and gRNA design.
KEY RESPONSIBILITIES
  • Drive the strategy and success of projects that enable diagnostic research teams to design experiment, access their data, and generate robust analyses
  • Identify and implement new technologies that enable the Bioinformatic team to provide design and analysis tools to wet lab scientists
  • Facilitate sample tracking and improve team user experience in Benchling ELN
  • Develop SOPs and other documentation for internal software validation and follow best practices for software development in regulated environments
  • Manage team of bioinformaticians, data scientists, data engineers, and software engineers to deliver on project goals
  • Prepare data and content for presentations, white papers, or other company-relevant materials

REQUIRED QUALIFICATIONS
  • PhD in bioinformatics, computer science, computational biology or related field and 4 years of industry experience (Sr. Manager) or 5 years of industry experience (Associate Director)
  • Experience leading bioinformatics and/or software teams
  • Proficiency with Python, R, SQL, and tools/libraries for data analysis
  • Experience working with cloud environments (i.e. AWS)
  • Extensive experience in bioinformatics tool and pipeline development
  • Experience working with Github

PREFERRED QUALIFICATIONS
  • Understanding of multiplex primer design requirements for PCR and isothermal assays
  • Experience with analyzing viral diversity (e.g. SARS-CoV-2)
  • Experience working and developing bioinformatics production systems
  • Familiarity with CRISPR-Cas literature
  • Knowledge of statistical methods and mathematical models in the interpretation of biological data
  • Experience working on the development of diagnostic assays (510(k), CE-IVD)
  • Strong communication, data visualization, and organization skills 

BENEFITS
  • Company-paid health/vision/dental benefits
  • Unlimited vacation and generous sick time
  • Company-sponsored meals and snacks
  • Wellness, caregiver and ergonomics benefits
  • 401(k) with company matching

Mammoth Biosciences is harnessing the diversity of life to power the next generation of CRISPR products. Through the discovery and engineering of novel CRISPR systems, the company is enabling the full potential of its platform to read and write the code of life. Mammoth aims to develop permanent genetic cures through best-in-class in vivo and ex vivo therapies and to democratize disease detection with on-demand diagnostics. Mammoth can provide enhanced diagnostics and genome editing for life science research, healthcare, agriculture, biodefense and more. Based in the San Francisco Bay Area, Mammoth Biosciences is co-founded by CRISPR pioneer and Nobel Laureate Jennifer Doudna and Trevor Martin, Janice Chen, and Lucas Harrington. The firm is backed by top institutional investors including Redmile Group, Foresite Capital, Senator Investment Group, Sixth Street, Decheng, Mayfield, NFX, and 8VC, along with leading individual investors including Brook Byers, Tim Cook, and Jeff Huber.

TEAM
The Diagnostics team is advancing our CRISPR-based DETECTR® platform to address unmet needs across the continuum of testing. From laboratories to the home, our mission is to democratize diagnostics with CRISPR. 

It is our policy and intent to provide equal opportunity to all persons without regard to race, color, religion, political affiliation, sex/gender (including gender expression/identity, pregnancy, childbirth and related medical conditions), marital status, registered domestic partner status, sexual orientation, age, ancestry, national origin, veteran status, disability, medical condition, genetic characteristics, and/or any other basis protected by law.  This policy covers all facets of employment including, but not limited to: recruitment, selection, placement, promotions, transfers, demotions, terminations, training, and compensation.

Mammoth Biosciences requires that all employees be vaccinated against COVID-19 as a condition of at-will employment, with exceptions for medical or religious reasons in compliance with local, state, and federal law. 

Company

Mammoth Biosciences is a biotechnology company focused on leveraging its proprietary ultracompact CRISPR systems to develop long-term curative therapies, as well as other applications such as decentralized precision diagnostics. Founded by CRISPR pioneer and Nobel laureate Jennifer Doudna and Trevor Martin, Janice Chen, and Lucas Harrington, the company’s ultracompact proteins are designed to enable in vivo gene editing in difficult to reach tissues utilizing both nuclease applications and new editing modalities beyond double stranded breaks, including base editing, gene writing, and epigenetic editing. The company is building out its pipeline of potential in vivo gene editing therapeutics and capabilities and has partnerships with leading pharmaceutical and biotechnology companies to broaden the reach of its innovative and proprietary technology. Mammoth’s deep science and industry experience, along with a robust and differentiated intellectual property portfolio, have enabled the company to further its mission to transform the lives of patients and deliver on the full promise of CRISPR technologies.

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Company info
Website
Phone
(650) 294-8583
Location
South San Francisco
CA
94080
United States

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