Biological Scientist

Bethesda, Maryland
Jun 28, 2022
Required Education
Position Type
Full time

We are currently searching for a Biological Scientist to provide technical and laboratory support to the Neuropathology Unit at NINDS. This opportunity is full-time, and it is on site in Bethesda, MD.  

Duties & Responsibilities
  • Follow established procedures and regulations for procurement, handling, and storage of patient tissue and fluid specimens resulting from clinical research protocols
  • Monitor biorepository database entry including specimen inventory, tracking and documentation of usage, freezer status, and other required record keeping
  • Participate in FDA audits of specimen storage and tracking relating to clinical trials
  • Collect and analyze biological data about relationships among and between organisms and their environment
  • Monitor and observe experiments, recording production and test data for evaluation by research personnel
  • Study basic principles of plant and animal life, such as origin, relationship, development, anatomy, and function
  • Analyze experimental data and interpret results to write reports and summaries of findings
  • Perform a variety of standard molecular biology and biochemical techniques such as PCR, DNA cloning and plasmid production, transfection, gene expression silencing, gene editing, gel electrophoresis, and Western blotting
  • Perform standard cell culture techniques including cryopreservation
  • Establish primary cell cultures by mechanically and/or enzymatically dispersing normal and tumorous tissue
  • Perform various functional assays on cultured cells (e.g., proliferation, invasion, regulation of gene expression/differentiation
  • Perform small animal husbandry including mouse colony maintenance and genotyping; ad-here to and update IACUC protocols
  • Operate, calibrate, or maintain equipment used in quantitative or qualitative analysis, such as spectrophotometers, calorimeters, flame photometers, or computer-controlled analyzers
  • Maintain and operate laboratory equipment to analyze samples and laboratory findings
  • Monitor and ensure the smooth functioning of the laboratory by tracking and ordering supplies in a timely fashion, keeping laboratory equipment in good working order
  • Arrange for routine equipment maintenance and repairs, and for staff training on specialized equipment
  • Serve as point of contact for facility and space issues, safety inspections
  • Perform standard histology techniques including tissue processing, staining, immunohistochemistry, and immunofluorescence
  • Monitors and maintain histology-related equipment such as a cryostat, automated stainer, digital slide scanner, fluorescent and brightfield microscopes
  • Develop and optimize new immunohistochemistry protocols when necessary
  • Collect and maintain accurate and complete records for the Biospecimen Bank, for clinical trial specimens, and for all experimental procedures and results
  • Maintain up-to-date descriptions of project methodologies, which descriptions may be incorporate into resulting publications or procedure manuals
  • Program and use computers to store, process, and analyze data
  • Monitor operational procedures in technical environments to ensure conformance to standards
  • Interpret, record, and/or research operational data
  • Provide consultation, training, and guidance to other personnel (e.g., neurosurgery residents, students, postgraduate fellows, collaborators from other laboratories) in the principles and use of specialized techniques and equipment






  • The ability to work both independently and as part of a team, possession of excellent time management and organizational skills, and the ability to multitask and shift priorities when required
  • Excellent written and oral communication skills
  • Proficiency in record keeping and computer skills, including working with spread sheets/databases
  • Knowledge of BSL-2 precautions for handling clinical specimens
  • Experience in histology and immunohistochemistry techniques
  • Several years of laboratory experience in biology lab skills (cell culture, molecular biology, and small animal husbandry)
  • Microsoft Office Expertise
  • Minimum Education: Master’s Degree in Biology or related discipline
  • At least 1-2 years of specialized experience


Due to our contractual requirements and federal orders, including an Executive Order from the White House and an emergency regulation from the Centers for Medicare & Medicaid Services (CMS), the position for which you are applying requires that you provide proof of your vaccination status. If you are unable to receive the COVID-19 vaccine for medical reasons or because of a sincerely held religious belief, you may request an exemption from the vaccination requirement which shall be reviewed after the submission of requested documentation. If an accommodation is granted, the conditions may include weekly testing and masking. All Guidehouse employees also agree to follow any additional health and safety mitigation policies that may be required in the workplace.


Company Description

Dovel Technologies and its Family of Companies (Medical Science & Computing and Ace Info Solutions) was acquired in October 2021.


Guidehouse is a leading global provider of consulting services to the public sector and commercial markets, with broad capabilities in management, technology, and risk consulting. By combining our public and private sector expertise, we help clients address their most complex challenges and navigate significant regulatory pressures focusing on transformational change, business resiliency, and technology-driven innovation. Across a range of advisory, consulting, outsourcing, and digital services, we create scalable, innovative solutions that help our clients outwit complexity and position them for future growth and success. The company has more than 12,000 professionals in over 50 locations globally. Guidehouse is a Veritas Capital portfolio company, led by seasoned professionals with proven and diverse expertise in traditional and emerging technologies, markets, and agenda-setting issues driving national and global economies.


Guidehouse is an Equal Employment Opportunity / Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, national origin, ancestry, citizenship status, military status, protected veteran status, religion, creed, physical or mental disability, medical condition, marital status, sex, sexual orientation, gender, gender identity or expression, age, genetic information, or any other basis protected by law, ordinance, or regulation.


Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance, including the Fair Chance Ordinance of Los Angeles and San Francisco.


If you have visited our website for information about employment opportunities or to apply for a position, and you require accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.


Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse, and Guidehouse will not be obligated to pay a placement fee.