Upstream Process Development Associate

Bethesda, Maryland
Jun 28, 2022
Required Education
Masters Degree/MBA
Position Type
Full time

We are currently searching for an Upstream Process Development Associate to provide support to the National Institutes of Health (NIH). This opportunity is a full-time position with MSC and it is onsite in Bethesda, MD.


Duties & Responsibilities
  • Support vaccine development initiatives, including the production of vaccines for Phase 1 and 2 vaccine trials.
  • Involved in the development of scalable fermentation and purification processes for production of recombinant malaria antigens produced by Escherichia coli or Pichia pastoris.
  • Small-scale and pilot-scale (60L) fermentation development.
  • Analysis of approaches for harvesting, purification development of scalable procedures
  • Support to the analytical effort.
  • Other duties include preparing various media, buffers, stock supplies, and other reagents for use in the laboratory.


  • B.S. degree in molecular biology, biochemistry or related field and three or more years of related experience, or an M.S. degree in a similar field with one or more years of related experience. 
  • Knowledge of current Good Laboratory Practices and current Good Manufacturing Practices
  • Knowledge of FDA drug approval process\
  • Experience preparing laboratory protocols
  • Experience with vaccine research and development preferred\
  • Experience using New Brunswick fermenters, Akta Explorers and/or Pilot, or equivalent equipment is essential. 
  • Experience with Western blotting procedures, endotoxin testing and other HPLC/UPLC methods would be an advantage.  
  • Strong computer skills including experience with Microsoft Word, PowerPoint, Excel and graphics programs.
  • Excellent verbal and written communication skills.


Company Description

Dovel Technologies and its Family of Companies (Medical Science & Computing and Ace Info Solutions) was acquired in October 2021.


Guidehouse is a leading global provider of consulting services to the public sector and commercial markets, with broad capabilities in management, technology, and risk consulting. By combining our public and private sector expertise, we help clients address their most complex challenges and navigate significant regulatory pressures focusing on transformational change, business resiliency, and technology-driven innovation. Across a range of advisory, consulting, outsourcing, and digital services, we create scalable, innovative solutions that help our clients outwit complexity and position them for future growth and success. The company has more than 12,000 professionals in over 50 locations globally. Guidehouse is a Veritas Capital portfolio company, led by seasoned professionals with proven and diverse expertise in traditional and emerging technologies, markets, and agenda-setting issues driving national and global economies.


Guidehouse is an Equal Employment Opportunity / Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, national origin, ancestry, citizenship status, military status, protected veteran status, religion, creed, physical or mental disability, medical condition, marital status, sex, sexual orientation, gender, gender identity or expression, age, genetic information, or any other basis protected by law, ordinance, or regulation.


Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance, including the Fair Chance Ordinance of Los Angeles and San Francisco.


If you have visited our website for information about employment opportunities or to apply for a position, and you require accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.


Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse, and Guidehouse will not be obligated to pay a placement fee.