Senior Process Development Engineer I, Cell Therapy
Why Join Intellia?
Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.
Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done.
We wantall ofour people to go beyond what is possible. We aren’t constrained by typical end rails, and we aren’t out to just “treat” people. We’re all in this for something more. We’re driven to cure and motivated for change. Just imagine the possibilities of what we can do together.
How you will Achieve More with Intellia:
You will join the growing Tech Ops team in the cell therapy process development function, contributing to the development and scale-up of robust manufacturing processes. In this critical role, you will collaborate to develop and characterize processes for Intellia’s ex vivo pipeline within defined timelines. You will be responsible for the execution and optimization of our full-scale non-GMP in-house production activities. Other responsibilities include: Drive and executing process development and scale-up activities to ensure robustness and scalability of autologous and allogeneic cell therapy processes for successful tech transfer to CDMOs
Perform reproducible development runs and generate high-quality drug product material to support other Intellia internal needs, i.e., preclinical studies and analytical development
Support tech transfer of our processes to CDMOs, including training, troubleshooting, and protocol and batch record review and serve as a strong technical presence to ensure our programs’ success
Contribute to documentation requirements, including reports and regulatory documents to support future regulatory filings
You are a driven process engineer with experience in cell therapies, including engineered T cell therapies. You are knowledgeable about manufacturing autologous and allogeneic cell processes, including standard cell therapy manufacturing equipment and unit operations. You have demonstrable experience in the development of robust, reliable processes for complex cellular products. You are willing to be a strong voice with CDMOs to effectively transfer processes and resolve problems. You are collaborative by nature and comfortable in a fast-paced environment with competing priorities. Other qualifications include:
Degree in chemical or biological engineering or related field
Demonstrable experience in scale-up and process engineering of cell therapies within closed systems
Sound understanding of cell therapies, ideally engineered T cell therapies, as evidenced by 8+ years of hands-on experience in cell therapy process development of autologous or allogeneic products, or Ph.D. and 0-3 years of experience
Experience with operation and optimization of cell therapy unit operations, including CliniMACS, LOVO, Sepax, Xuri, etc.
Skilled in characterization and analytics of cell therapy products, including cell counts and flow cytometry
Previous experience in tech transfer, including CDMO interactions
Meet your future team:
You will join a high-performing, collaborative, and enthusiastic Cell Therapy Process Development team within the Tech Ops organization that supports Intellia’s ex vivo pipeline. The team is a rapidly growing group of engineers and scientists who work seamlessly together to develop robust processes for our cell therapy programs. In our team, we encourage asking questions, taking risks, and we look forward to nurturing your professional growth and development.
This is a key role that will interface with stakeholders in our CDMOs and internal teams, including external manufacturing and supply chain, analytical development, preclinical development as well as the Cell Therapy Process Development team. You will join a new group within the larger team to support our ex vivo process engineering and scale-up efforts.
Covid-19 Vaccination Policy: All Intellia employees, regardless of work location, must be fully vaccinated for COVID-19. This requirement includes a booster dose once eligible. Requests for exemption for medical or sincerely held religious beliefs will be considered.
EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.