Senior Scientist, Purification

Just is seeking a motivated and creative scientist or engineer who desires a significant opportunity to improve worldwide access to biotherapeutics. As a downstream design scientist/engineer, you will join a fast-paced, collaborative, and multidisciplinary team to develop purification processes for low-cost biotherapeutic manufacturing. Process design at Just-Evotec means exposure to innovative technologies like high throughput automated robotic screening and continuous processing technologies for a first-of-its-kind flexible and reconfigurable manufacturing facility. The successful candidate will have experience in chromatography and filtration theory and operations. Experience with high throughput chromatography screening, chromatography mechanistic modeling, multicolumn chromatography and/or process modeling is a plus. The ideal candidate has strong written and verbal communications skills, works well independently and in teams, and continually looks for ways to improve processes and technology.

Responsibilities:

• Develop early and late phase purification processes for biotherapeutics manufacturing
• Technology development to reduce the cost and improve the efficiency of purification processes
• Transfer processes to clinical and commercial manufacturing facilities
• Technology development to reduce the cost and improve the efficiency of purification processes
• Participation in process and technology development teams
• Technical document authoring including regulatory documents
• Mentor junior staff

Position Requirements:

• BS degree in Engineering, Biochemistry or related field and 10+ years of experience, MS with 5+ years of experience or PhD with 3+ years of experience
• Knowledgeable in chromatography and filtration theory, downstream development, and scale-up strategy
• Experience with chromatography operations including using Akta systems
• Experience with filtration operation including executing bench-scale dead-end filtration, viral filtration, and UF/DF
• Comfort with being functional area lead on integrated project teams
• Excellent experimental design and analysis skills
• Desire to work in a fast, collaborative, and team-oriented environment
• Strong oral and written communication skills

Additional Preferred Qualifications:

• Experience with design of experiments (DOE) and analysis using statistical software packages (JMP, MATLAB, etc.)
• Experience with automation method development and operation using robotic liquid handling systems and high throughput chromatography resin screening
• Experience with multi column chromatography
• Experience with process modeling and chromatography mechanistic modeling
• Experience with early & late-stage regulatory filing
• Experience in participating in CMC teams