Senior Engineer / Senior Scientist

Andover, Massachusetts
Jun 24, 2022
Required Education
Bachelors Degree
Position Type
Full time


A key member of the MSAT Andover Upstream Processing Team with responsibilities for leading the fermentation processes and technologies

  • Execution of complex experimental designs, and oversee interpretation of large data sets, including multifactorial experimental design
  • Assist with manufacturing investigations and process troubleshooting
  • Assist with technology transfers to cGMP facilities
  • Ensure a Continuous Improvement Mindset within the Upstream team
  • Maintain the depth and scientific capability of the fermentation Team. Promote and drive the technical and personal development of peers and juniors
  • Experience in drafting regulatory dossiers for agency submission and responding to queries
  • Ensure the group work safely at all times.
  • Stay current with, and apply, all good work safety practices as recommended by the Andover site, the Biopharma Operating unit, and the company


  • PhD with 0-4 years, MS with 5-8 years, or BS with 7 years of experience in a scientific / technical role within the biotech industry supporting the development and commercialization of therapeutic recombinant proteins or vaccines
  • Previous experience in designing and executing components of major experimental programs for biologics drug substance production in the laboratory or pilot-plant setting.
  • Proficient user of problem-solving, risk analysis and statistical tools
  • Highly proficient in common upstream bioprocessing tools with considerable experience in associated transfer and scale up. Knowledge of all aspects of fermentation, including batch, fed-batch, perfusion and harvest/clarification operations; control and data acquisition systems.
  • Experienced in use of Design of Experiment (DoE) methodology and associated software (JMP, MiniTab) and other statistical tools
  • Hands-on familiarity with drug regulations/regulatory processes and quality/GMP/compliance systems of the pharmaceutical industry.
  • Experience in drafting regulatory dossiers for agency submission


  • Experience in supporting scale-up and technology transfer to pilot or commercial scale facilities
  • Experience with protein and carbohydrate chemistry is strongly desired
  • Proficient in benchtop and up to 20 L Steam in place bioreactor operations

Behavioral attributes

  • Consultative, open andtransparent, with a self-assured bias towards decision making and action when circumstances demand.
  • Highly motivated with a drive towards technical achievements of self and team.
  • Excellent communication skills (verbal + written).
  • Ability to matrix-work effortlessly across team and organizational / hierarchical boundaries


  • May require occasional off- hour working for participation in teleconferences with other global sites.
  • Some travel may be required, but is not expected to be a standard aspect of role (<5% time)
  • Must be able to lift 25 lbs

Work Location Assignment:On Premise


Ability to lift 25 lbs

Ability to preform complex data analysis

Ability to communicate and work on teams


  • May require occasional off- hour working for participation in teleconferences with other global sites.
  • Some travel may be required, but is not expected to be a standard aspect of role (<10% time)

Additional Job Information

  • Last day to apply: July 20th 2022
  • Relocation assistance available

Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development