Scientist / Senior Scientist, Nonclinical Development (In Vivo)

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Adicet Bio, Inc is a clinical stage biotechnology company discovering and developing allogeneic gamma delta T cell therapies for cancer. We are advancing a pipeline of “off-the-shelf” gamma delta T cells, engineered with chimeric antigen receptors (CAR) and T cell receptor-like antibodies (TCRL), to enhance selective tumor targeting, facilitate innate and adaptive anti-tumor immune response, and improve persistence for durable activity in patients. Our approach to activate, engineer and manufacture allogeneic gamma delta T cell product candidates derived from the peripheral blood cells of unrelated donors allows us to generate new product candidates in a rapid and cost-efficient manner. For more information, please visit our website at http://www.adicetbio.com.

SCIENTIST / SENIOR SCIENTIST, NONCLINICAL DEVELOPMENT (IN VIVO)

We are currently seeking a highly motivated candidate with a strong immunology background to join our pharmacology team.

Key Responsibilities:

• Work closely with multiple functional groups in the efforts to progress immune cell-based cancer therapies to the clinic.
• Design, conduct, and manage in vivo and ex vivo experiments to evaluate Adicet’s immune cell platforms, such as anti-tumor efficacy, in vivo phenotyping, cell trafficking, distribution and persistence in animal models.
• Support biomarker discovery and translational studies for Adicet’s clinical candidates through in vivo modeling.
• Perform hands-on work when needed, including animal model handling, in vivo data collection and ex vivo analyses of blood and organ/tumor tissues.
• Manage and analyze experimental data, interpret results and prepare presentations for internal and external meetings, regulatory filings and publications.
• Provide scientific inputs and contribute intellectually to the organization success.
• Manage and direct daily work of junior research staff.
• Maintain detailed documentation of procedures and data to comply with internal quality criteria.

Qualifications:

• PhD in Immunology or relevant biological sciences with an immuno-oncology research background.
• A minimal two years of postdoctoral research experience, preferably in an industry setting.
• Previous hands-on experience in murine tumor models including xenograft and/or syngeneic models is required.
• Must demonstrate experience in establishing, executing and interpreting in vivo experiments in oncology research and technical excellence in murine tumor models.
• Experience in ensuring quality studies and accurate analysis of in vivo data is required.
• Previous hands-on experience in multi-color flow cytometry and independently analyzing the data using analytical software such as FlowJo is required.
• Previous hands-on experience in in vivo bioluminescence and/or fluorescence imaging workflow and data analysis is preferred.
• Experience in working knowledge of immunohistochemistry and data interpretation is a plus.
• Demonstrate scientific creativity, critical thinking, and analytical problem-solving skills, with a strong track record of research productivity as evidenced by high-quality publications.
• Ability to work efficiently and independently under minimal supervision in a dynamic team environment.
• Previous management experience is preferred.
• Excellent written and verbal communication skills.

Adicet Bio requires all workers to be fully vaccinated against COVID-19, including the booster dose.

Benefits:

Adicet Bio offers both comprehensive benefits and Paid Time (PTO) plans for employees, which begin on the first day of employment, as well as the opportunity to work in a growing, dynamic environment.

Adicet Bio is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.