Drug Discovery Scientist - Computational ADME/TOX Prediction
Schrödinger aims to revolutionize drug discovery through the use of breakthrough computational methods. We deploy these methods both through software sales and by using them to advance our own internal drug discovery efforts. Our structure-based algorithms for drug discovery are used across the pharmaceutical industry, and these tools have enabled four of the programs pursued by our internal drug discovery group to progress into the clinic in the last seven years. Two are still progressing through trials, and two have been approved by the FDA.
We're seeking a highly-motivated scientist with experience in structure-based ADME/TOX predictions to join the team and help us to better predict these important properties.
Who will love this job:
A computational chemist who enjoys looking beyond on-target affinity to the host of other properties that are required for a successful small molecule drug discovery, such as bioavailability, CNS penetration, clearance, hERG inhibition, clearance, etc.
A researcher who has a track record of developing or expanding methods to determine these properties in silico and a desire to learn new approaches to the problem
A proficient coder who has experience using python or other programming languages to implement algorithms and test hypothesis
What you’ll do:
Combine physics-based modeling, medicinal chemistry knowledge, machine learning, and a wealth of experimental data to create and validate new technologies for the prediction of ADME/TOX properties
Work with our drug discovery group to deploy these new technologies to active projects
What you’ll need:
PhD in computational chemistry, biochemistry, biophysics, or a related field
Peer-reviewed publications in the field
Experience with python or another programming language
Pay and perks:
Schrödinger understands it’s people that make a company great. Because of this, we’re prepared to offer a competitive salary, stock options, and a wide range of benefits that include healthcare (with dental and vision), a 401k, pre-tax commuter benefits, a flexible work schedule, and a parental leave program. We have catered meals in the office every day, a company culture that is relaxed but engaged, and over a month of paid vacation time. Our Administrative and Human Resources departments also plan a myriad of fun company-wide events. New York is home to our largest office, but we have teams all over the world. Schrödinger is honored to have been selected as one of Crain's New York Best Places to Work in 2018 and 2019.
Sound exciting? Apply today and join us!
As an equal opportunity employer, Schrödinger hires outstanding individuals into every position in the company. People who work with us have a high degree of engagement, a commitment to working effectively in teams, and a passion for the company's mission. We place the highest value on creating a safe environment where our employees can grow and contribute, and refuse to discriminate on the basis of race, color, religious belief, sex, age, disability, national origin, alienage or citizenship status, marital status, partnership status, caregiver status, sexual and reproductive health decisions, gender identity or expression, sexual orientation, or any other protected characteristic. To us, "diversity" isn't just a buzzword, but an important element of our core principles and key business practices. We believe that diverse companies innovate better and think more creatively than homogenous ones because they take into account a wide range of viewpoints. For us, greater diversity doesn't mean better headlines or public images - it means increased adaptability and profitability.