Research Associate/Sr. Research Associate – In Vivo Pharmacology

Position Title: Research Associate/Sr. Research Associate

Position Level: Century Associate Level (CAL)

Reports to: Senior Associate Scientist

Company Background:

Century Therapeutics is developing novel allogeneic living cell products for oncology that overcome the limitations of current cell therapies. Century's genetically-engineered, universal iPSC-derived immune effector cell products are designed to specifically target hematologic and solid tumor cancers. Our commitment to developing off-the-shelf cell therapies will expand patient access and provide an unparalleled opportunity to advance the course of cancer care.

Century's foundational technology is built on induced pluripotent stem cells (iPSCs) that have unlimited self-renewing capacity. This enables complex cellular engineering to produce controlled cell banks of modified cells that can be expanded and differentiated into desired immune effector cells, which can supply vast amounts of allogeneic, homogeneous therapeutic products. This platform differentiates Century from other approaches that utilize non-renewable donor-derived cells.

Role:

Century is looking for a motivated and experienced Sr. Research Associate or Research Associate to advance the growing and promising field of cell therapy to treat cancer. She/he will actively participate in conducting in vivo experiments ranging from early-stage discovery to late-stage preclinical studies. The ideal candidate will have experience with cell therapy approaches and familiarity with standard immunological lab techniques related to immuno-oncology. She/He will work closely with scientists within the group and collaborate with other functional groups at different Century sites to achieve company-aligned goals. This position is based in our Hamilton, Ontario laboratory.

This position is based in Hamilton, Ontario, Canada.

Responsibilities:

• Independently execute oncology in vivo studies, in accordance with Ethical Committee protocols
• Manage multiple experiments simultaneously
• Maintain tissue culture or human tumor cells
• Prepare, collect, and process biological samples such as peripheral blood and splenocytes
• Maintain accurate research records and deliver scientific presentations and reports internally to interdisciplinary teams
• Liaise with vivarium facility staff
• Contribute to general laboratory maintenance
• Interact with off-site research teams on program-specific activities
• Foster a collaborative and scientifically rigorous team culture

Qualifications:

• Non-PhD. position
• Senior Research Associate: BSc. in a biological sciences field with 3+ years of experience, or MSc. in a relevant field with 1+ years of experience
• Research Associate: BSc. in a biological sciences field with 1+ years of experience, or a MSc. in a relevant field
• Industry experience preferred
• Knowledge of in vivo oncology preclinical model design, execution, and evaluation
• Hands-on experience with tumor xenograft studies, ideally with CNS cancers
• Knowledge of ex vivo analysis endpoints and methodology
• Experience with optical imaging modalities
• Highly proficient and independent in the lab

Requirements:

• Experience with small animal dosing and/or surgeries, health monitoring, and data collection
• Ability to work independently, be pro-active, remain organized, and conduct/prioritize multiple projects in a fast-paced start-up environment
• Open-minded and risk-tolerant; humble and not afraid to push and be challenged
• Excellent oral and written communication skills; strong problem-solving and analytical skills
• High scientific integrity committed to ethics and scientific rigor

Century Therapeutics Inc. is an Equal Employment Opportunity/Affirmative Action Employer - Minority/Female/Disability/Veteran. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or veteran status or any other characteristic protected by federal, state, or local law.