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Downstream Process Scientist

Employer
GreenLight Biosciences, Inc.
Location
Medford, MA
Start date
Jun 17, 2022

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ABOUT GREENLIGHT

At GreenLight we are working to solve two of the world's greatest problems: global food insecurity and equal access to vaccines and the associated health benefits. Unlike most corporations who can be required to put profits ahead of other principles, GreenLight is one of the first Public Benefit Corporations to be publicly traded and have a charter that requires a focus on how it benefits its employees, community and society and has a broad portfolio addressing key issues in plant health and human health (Nasdaq: GRNA) by leveraging the full potential of dsRNA and mRNA. The GreenLight team is over 300 people across our headquarters in Medford, MA, an R&D facility in Woburn, MA and an R&D facility in Research Triangle Park, NC. GreenLight also has a biomanufacturing plant in Rochester, NY. Initiatives include finding ways to support biodiversity, protect bees and other pollinators, treat rare diseases as well as develop vaccines.

At GreenLight, we believe inclusion is the way forward. We celebrate the power of working together to address humanity’s challenges, meet the needs of underserved populations, and push the boundaries of scientific discovery. Fueled by our aspiration for a true sense of belonging, our talented teams embody the principles of diversity and equality as we strive to bring food security, medicine, and healthcare to everyone—paving the way for a sustainable future. For more information, visit www.greenlightbio.com.

GreenLight Biosciences seeks Downstream Process Scientist in Medford, MA. Assist in producing drug products for preclinical studies in support of manufacturing process development and preclinical discovery: develop/implement downstream purification processes for mRNA product purification including multiple chromatographic separations, solid phase extractions, and filtration; purification of mRNA products including documentation in ELN/QMS, troubleshooting, in-process analytics and final QA/QC; schedule/track DSP operations; adapt/scale up new downstream unit operations; perform multiscale column packing/validation; evaluate downstream process robustness; develop novel processes and analytical methods; analyze/present experimental results/recommendations; author/review SOPs, sample reports, and ELN records; mentor junior team members. Reqs: Master’s in Chemical Engg, Pharmaceutical Science, Biochemistry, Analytical Chemistry or equiv field and 4 yrs exp in process development in biopharma or biotech industry (in alternative, will accept PhD and 2 yrs), including 2 yrs working in GLP or GMP/cGMP environment (exp can be gained concurrently). Knowledge of: chromatographic separation method development, multiple chromatography modes, column packing/validation, AKTA purification systems and Unicorn software; downstream processing operations such as clarification methods for cell culture, ultrafiltration, diafiltration, tangential flow filtration, depth filtration, flocculation, and centrifugation; cell or microbial culturing, scale up, high-throughput screening using DOE approaches; molecular biology techniques such as PCR, gel electrophoresis and SDS PAGE; analytical techniques such as HPLC, LC-MS, capillary electrophoresis (using tools such as Agilent Fragment analyzer, Agilent BioAnalyzer, Lab Chip), Octet, HIC, and ELISA. By resume to hr@greenlightbio.com.

Greenlight Biosciences Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.

GreenLight requires proof of COVID-19 vaccination for its employees.

 

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