Associate Director, Early Clinical Development AI/ML

Cambridge, MA
Jun 15, 2022
Required Education
Position Type
Full time


Worldwide Research, Development, and Medical (WRDM) is recruiting a team experienced in clinical uses of artificial intelligence (AI), machine learning (ML) and predictive modeling. The successful candidate will help us derive insights from Pfizer’s proprietary data and external data to generate hypothesis focused on clinical development and precision medicine approaches. This focus will be on testing strategies for patient segmentation and potential subpopulations. The candidate will partner with clinical experts and research unit scientists to drive decision making using contemporary AI/ML models and architecture. They will have expertise in biomarker analysis, computer science, computational analytics, data science and/or statistics focused on experience in building and using AI/ML techniques to solve complex problems. Experienced in working on clinical stage assets and precision medicine strategies a plus. The candidate should be familiar with proposing, developing, testing and validating AI/ML tools for use across multiple therapeutic areas. They will also partner with multiple clinical, computational, digital and biological functions to build datasets and implement algorithms for endpoint selection, individualized dosing strategies and/or patient stratification. Understanding of data infrastructure is a plus to work with Digital colleagues on appropriate data repositories and analytical tools. The successful candidate will work within internally and externally to bring the latest solutions and technology to Pfizer.


  • Use appropriate approaches from data collection/aggregation through model building and deployment to ensure robust performance for all predictive algorithms.
  • Apply cutting edge AI/ML methods to clinical development efforts
  • Collaborate with internal and external groups to build datasets to evaluate potential biomarkers for model building.
  • Work in cross-functional teams to understand scientific questions and potential data needed for precision medicine approaches
  • Prototype, train, validate and deploy novel AI/ML models for patient selection strategies for clinical assets in collaboration with multiple functions across WRDM and Pfizer’s Digital organization.


Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.


  • PhD in statistics, computer science, applied mathematics, scientific machine learning, computational genomics or related discipline with 2 years of relevant experience
  • 2 years of programming experience in Python, R, Perl, Java, julia, etc.
  • 2 years of experience in design, development and deployment of solutions using AI/ML approaches
  • Knowledge and experience with common AI/ML algorithms
  • Demonstrated interpersonal and communication skills to collaborate with multiple functions in a matrixed organization
  • Ability to independently contribute to cross-functional teams
  • Familiarity with high-dimensional datasets and analyses, preferably with clinical, biomarker, real-world data and/or PK/PD data sets
  • Experience with high performance computing environments and cloud computing platforms


Eligible for Relocation Package

Eligible for Employee Referral Bonus


Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

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