Vice President, Clinical Development (Solid Tumor/Lung Cancer Disease Area)

Fate Therapeutics is seeking a highly motivated hands-on physician leader to serve as a Vice President overseeing our solid tumor franchise in Fate’s Clinical Development Group. This position will lead Fate’s cellular immuno-oncology program(s) in the disease area of solid tumors, with a focus on developing a broad early- and late-stage development strategy in lung cancer. This individual will develop and implement clinical strategies and be responsible for the oversight of contracted personnel and/or organizations to advance Fate’s clinical program(s). He or she will also serve as a liaison between Fate and clinical investigators and will maintain established and productive relationships with key opinion leaders and Health Authority representatives. The ideal candidate must have experience and subject matter expertise in solid tumors including in-depth knowledge and experience in lung cancer, with experience and expertise in the design and conduct of early and late-stage clinical studies.  Experience with cellular therapies is desirable. This is a full-time position reporting to the Chief Medical Officer and is based at the Company’s corporate headquarters in San Diego, California or at our location in the San Francisco Bay area. 
Responsibilities

• Provide clinical leadership of a comprehensive and integrated Clinical Development Plan for individual immuno-oncology programs from first-in-human studies through registrational studies.
• Formulate study designs, lead protocol development, and collaborate with cross-functional teams in study start-up activities in collaboration with clinical investigators, key opinion leaders and Health Authorities.
• Have direct involvement in all aspects of study conduct, in collaboration with Fate clinical development and contracted personnel, in the conduct of clinical activities including data review, analysis, and reporting that conforms to the highest ethical, safety and quality standards and in compliance with Fate, GCP and regulatory standards.
• Remain current on the therapeutic landscape in the relevant therapeutic areas through review of the scientific literature, interactions with key opinion leaders and other external experts and attendance at relevant scientific meetings, to provide input and guidance for the strategic direction of Fate programs.
• Participate as clinical contributor in Fate business development and investor-related activities.
• Play a key role in Health Authority interactions.
• Review available preclinical and clinical translational data that inform the design of future clinical trials.
• Attend and present at investigator meetings and site initiation visits as applicable.
• In collaboration with appropriate cross-functional team members actively engage in the preparation of Clinical Study Reports, Annual Reports and other safety reports, Health Authority pre-meeting packages, Investigator Brochures, and other periodic clinical reports.
• Collaborate with cross-functional groups to formulate publication strategy including active participation in authoring, preparation and review of manuscripts, conference abstracts and presentations and other external presentations of clinical data 

Qualifications

• M.D. and Board Certification or Board Eligibility in the field of Medical Oncology, with clinical experience and/or expertise in lung cancer.
• 10+ years of experience in clinical research including the design and execution of clinical trials, within a pharmaceutical or biotech environment.
• Experience in the development of immune oncology agents; experience in developing cell-based therapies is desirable.
• Experience in novel and innovative designs for early Phase studies; Phase 3 and/or registrational trial experience is a plus.
• Experience with U.S. and European Health Authority interactions and submission of clinical regulatory documents.
• Strong leadership skills with ability to work within and lead and motivate cross-functional matrixed teams.
• Strong written and verbal communication skills; willingness to engage with investigators, key opinion leaders and external advisors; and ability to effectively give presentations at conferences, advisory meetings, and other public forums.
• Engaged, results-oriented, hands-on, independent, and goal-oriented mentality; willingness to work in highly dynamic work environment and embrace uncertainty.
• Ability to multi-task and willingness to flexibly contribute simultaneously in multiple facets of drug development; willingness to learn new therapeutic areas.
• Self-motivation; good judgment; strong commitment to follow up on tasks and action items; organizational, analytical, and problem-solving skills; risk identification and management; creative and innovative thinking all highly desirable.
• Willingness to educate and mentor internal and external colleagues and collaborators.
• Ability and willingness to travel as required. 

Working Conditions and Physical Requirements

• May require occasional evening and weekend work.
• Full-time onsite work at Company’s headquarters in San Diego or in South San Francisco office.
• Minimum 10% time traveling to clinical sites and clinical/professional meetings. May include international travel. 

The preceding job description indicates the general nature and level of work performed by employees within this classification. Additional and incidental duties related to the primary duties may be required from time to time.

About Fate Therapeutics, Inc.
Fate Therapeutics is a clinical-stage biopharmaceutical company dedicated to the development of first-in-class cellular immunotherapies for patients with cancer. The Company has established a leadership position in the clinical development and manufacture of universal, off-the-shelf cell products using its proprietary induced pluripotent stem cell (iPSC) product platform. The Company’s immuno-oncology pipeline includes off-the-shelf, iPSC-derived natural killer (NK) cell and T-cell product candidates, which are designed to synergize with well-established cancer therapies, including immune checkpoint inhibitors and monoclonal antibodies, and to target tumor-associated antigens using chimeric antigen receptors (CARs). Fate Therapeutics is headquartered in San Diego, CA. For more information, please visit www.fatetherapeutics.com.