Frederick National Laboratory for Cancer Research

Research Associate I - Molecular Biology

Frederick, MD
Jun 14, 2022
Required Education
Bachelors Degree
Position Type
Full time

Research Associate I - Molecular Biology

Job ID: req2647
Employee Type: exempt full-time
Division: Cancer Research Technology Program
Facility: Frederick: ATRF
Location: 8560 Progress Dr, Frederick, MD 21701 USA

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc.  The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.


The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community. A major focus of the CRTP is the NCI RAS Initiative with the goal to discover new therapeutic interventions against RAS-driven cancers. As part of the RAS Initiative, the Protein Expression Laboratory (PEL) generates protein reagents to support internal and external RAS-related research.  PEL staff utilize a variety of cutting-edge protein production methods including expression in a wide variety of host platforms to generate high-quality protein reagents used for structural biology and drug discovery.


  • Perform basic microbiology techniques 
  • Carry out experiments, under the review of a scientist, in areas of microbial fermentation
  • Perform expression in bacterial culture systems including E. coli and V. natriegens
  • Generate small-scale protein purification data to enable optimization of protein production
  • Perform quality control on expression materials
  • Participate on project teams, present data and discuss experimental results


To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

  • Possession of a bachelor’s degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in biology, chemistry, biochemistry, or another field closely related to biomedical research.  Foreign degrees must be evaluated for U.S. equivalency
  • In additional to education requirements, a minimum of two (2) years of related biomedical experience is required
  • Ability to handle multiple scientific projects with a high degree of accuracy
  • Excellent oral and written communication skills
  • Ability to obtain and maintain a security clearance


Candidates with these desired skills will be given preferential consideration: 

  • Prior experience with microbial cell culture and sterile technique
  • Familiarity with high volume bacterial fermentation systems
  • Experience with small-scale protein purification technologies
  • Experience with Microsoft Office and Filemaker software


  • This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations

Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)