Senior Manufacturing Associate, Cell and Gene Therapy

Manager: Senior Manufacturing Manager
Department: Technical Operations
Location: Brisbane, CA

Sangamo Therapeutics is a genomic medicine company building value with cutting-edge work across four distinct but complementary technology platforms – gene therapy, cell therapy, in vivo genome editing, and in vivo genome regulation. Using its deep scientific expertise and proprietary zinc finger genome engineering technology, Sangamo is working to create genomic cures for patients suffering from severe genetic diseases for which today’s medicines can only treat symptoms. At Sangamo, we are passionate about transforming lives by building a robust, sustainable, differentiated, innovative, and high value genomic medicine pipeline that addresses patients with life-limiting conditions. Sangamo takes pride in being the first to edit endogenous human genes, first to treat patients with gene edited T cells, and first to treat patients with in vivo genome editing. Our top priority is to meet the needs of patients with commitment and compassion. Along with our commitment to science and to our patients, we also endeavor to create an inclusive environment that promotes and values diversity. Sangamo is a company where individuals can flourish, grow and develop their expertise.

We are seeking top talent to join our mission. Let’s build a better future together.

JOB SUMMARY:   
Sangamo Therapeutics is seeking a Manufacturing Associate or Senior Manufacturing Associate to contribute to the manufacture of gene and cell therapies for clinical trials and future commercial scale. This individual will perform and support daily upstream manufacturing processes in gene therapy as well as assist with both downstream gene therapy and cell therapy manufacturing. This role will also support incoming and outgoing technology and process transfers. This is an excellent learning opportunity to someone who wants to jump start their career in the cell and gene therapy industry.

ESSENTIAL FUNCTIONS: 

• Perform manufacturing processes including but not limited to cell culture thaw, cell culture maintenance and expansion, cell sampling, cryopreservation, transfection, bioreactor prep/inoculation and buffer/solution prep.
• Perform in-process quality testing using analytical instruments
• Write, review and revise Quality documents (SOPs, forms, batch records), as needed
• Consolidate and review process data and trends
• Generate and execute qualifications, as needed
• Support Sangamo’s Quality Management system including but not limited to deviation investigations and risk assessments

EDUCATION, EXPERIENCE AND SKILLS REQUIREMENTS:

• Minimum of Bachelor’s in Biology, Biochemistry or other relevant life science
• 0-2 years’ experience GxP in regulated lab environment
• Experience with cell culture (large scale and small scale, suspension or adherent) and/or purification techniques (filtration, column chromatography, etc.)
• Excellent communication skills such as providing cross-functional project updates, driving multi-department approvals, and informing management of blockers/delays
• Excellent aseptic technique
• Impeccable attention-to-detail
• Great time-management skills and ability to work in a fast-paced start-up environment
• Ability to analyze and resolve problems independently

OTHER QUALIFICATIONS: 

• Knowledge and/or experience with AAV and/or cell therapies a plus

Sangamo is an equal opportunity employer
The above reflects management’s definition of essential functions for this position but does not restrict the tasks that may be assigned. The above duties are representative only; management may assign or reassign duties and responsibilities to this position at any time.

COVID-19

Sangamo requires all U.S. workers to be fully vaccinated against COVID-19 as of their start date.  This requirement is a condition of employment at Sangamo, and it applies regardless of location or classification of role.  If you are unable to receive the vaccine, you will have an opportunity to request a reasonable accommodation consistent with applicable laws. 

Note to External Recruiters: Please understand that we do not accept unsolicited resumes from any source other than from the candidates themselves. Any agency or independent recruiter must have a signed copy of our agency agreement before presenting candidates. Submission of unsolicited resumes without our signed agreement will not create any implied obligation on our part.