Sr. Research Scientist II - Oncology Research

Foster City, CA
May 18, 2022
Required Education
Bachelors Degree
Position Type
Full time
Gilead Sciences (Foster City, CA) is seeking a talented and highly motivated Senior Research Scientist to join our Oncology Research group. Our collaborative and interdisciplinary research team utilizes state-of-the-art technologies and innovative methodologies to advance medicines into the clinic. The successful candidate is expected to lead and contribute to the discovery, research, and development of novel therapeutic agents to address unmet medical needs of cancer patients. S/he will have opportunities for career growth through acquisition of new skills, experiences, and professional relationships in a fast-paced and resource-rich environment.

Key Responsibilities

Lead the initiation and/or advancement of oncology projects into the pipeline using in vitro and in vivo methodologies
Participate in nomination of new targets
Direct, independently plan, execute, analyze, and interpret complex experiments to identify or validate novel targets, elucidate target biology, elucidate drug candidates' mechanism of action
Possess solid knowledge of in vivo pharmacology, pharmacokinetics, designing PK/PD/efficacy studies
Develop assays to measure pharmacodynamic markers, kinetics of drug response
Train and mentor junior scientists or direct members of project teams in the initiation and execution of experimental plans
Manage multiple projects simultaneously and work cross-functionally with colleagues in the oncology, bioinformatics, chemistry, DMPK and other relevant functions
Proactively evaluate new technologies and implement new approaches to enhance our understanding of disease mechanisms
Presents research findings and recommendations to leadership, author and contribute to research reports, manuscripts, IND and patent filings
Must think critically and creatively and be able to work independently, determine appropriate resources for resolution of problems and have strong organizational and planning skills
Cultivate a culture that embraces scientific excellence, urgency, partnerships with key stakeholders, continuous learning and improvement, taking proactive role in personal growth and development
Knowledge, Experience and Skills

PhD degree and 7+ years of experience after postdoctoral fellowship in Cell Biology, Molecular biology, or Immunology with a cancer-related focus or Bachelor's degree with extensive experience; Industry experience is desired
Deep and broad knowledge of cancer biology, targets and signaling pathways, demonstrated scientific rigor, independence and scientific achievements
Demonstrated experience in drug discovery and target identification / validation in oncology or immuno-oncology
Demonstrated experience in leading and advancing novel research programs from target identification through preclinical development
Excellent technical skills, extensive experience in general molecular and cell biology methods and superb knowledge of various experimental methodologies including but not limited to gene expression platforms, knockdown, knockout, knock-in and over-expression of genes, flowcytometry, MSD ELISA, high-content imaging
Technical skills applicable to chromatin biology is a plus
Experience managing projects at CROs is a plus
Attention to detail with excellent organizational and record keeping skills is a requirement
Excellent communication and interpersonal skills are required