Scientist I, Surface Chemistry

San Diego, CA
May 18, 2022
Required Education
Position Type
Full time

Please be aware that, as a condition of employment, proof of COVID vaccination is required for all U.S.-based employees (subject to limited exceptions).  To ensure the health and safety of all PacBio employees and our prospective candidates, we have instituted a virtual interview and onboarding experience.

Scientist I, Surface Chemistry

PacBio (NASDAQ: PACB) is a premier life science technology company that is designing, developing and manufacturing advanced sequencing solutions to help scientists and clinical research resolve genetically complex problems.  Our mission is to enable the promise of genomics to better human health. Genomics is core to all biological processes, and our advanced genomics tools provide scientists and clinical researchers the insights to better understand biology and health.  We are now entering the century of biology and genomics is at the heart of the next revolution.  Become part of the new paradigm in gene sequencing and help shape the future of genomic study by joining the PacBio team.

We are seeking a Scientist 1 to join our interdisciplinary Consumables Surface Chemistry team. Candidates must have a proven track record of problem solving, experimental design, and data analysis. The position will work collaboratively to help develop and characterize microfluidic surfaces for improved sequencing and expanded functionality. This is an excellent opportunity for fresh graduates and experienced research associates with experience in molecular biology, organic chemistry, surface science, or nanotechnology to learn new skills and apply their talents to a challenging and diverse set of problems.


  • Produce surface coatings for a variety of end uses through a variety of techniques
  • Characterize surfaces to determine coating properties
  • Structure surfaces according to proprietary technology
  • Work with scientists to plan and execute experiments
  • Work with scientists to develop meaningful process QCs
  • Collect and analyze data
  • Present and discuss data and results in meetings


  • B.S., M.S., or Ph.D in Chemistry, Chemical Engineering, Biochemistry, Bioengineering, or related field.
  • 4+ years of bench experience in an academic or industry research setting
  • Experience designing, organizing, and executing complex experiments, collecting data, and interpreting results.
  • Hands-on experience with relevant techniques in some or all the following areas:
    • Bioconjugation chemistry
    • DNA amplification
    • DNA origami
    • Surface characterization and metrology
    • Colloidal and/or polymer chemistry
    • Biochemical assays
    • Molecular Biology
  • Some experience in any of the following areas is a strong plus:
    • Microfluidics
    • Nanofabrication
    • Surface functionalization and passivation
    • Wet organic chemistry
    • Microscopy and biomolecular imaging
    • Next-generation sequencing
  • Strong written and verbal communication skills
  • Proficient with Excel, JMP and/or Python for analyzing and plotting data


  • Effective problem solver with a strong sense of curiosity and desire to learn
  • Enjoys highly interdisciplinary and collaborative work
  • Creative mindset
  • Thrives in a dynamic and fast paced environment
  • Loves executing experiments as much as generating and discussing data
  • Takes a rigorous first principles approach

All listed tasks and responsibilities are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional tasks and responsibilities.

All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability, gender identity, and sexual orientation.