Scientist II - Biology, Oncology Discovery

Location
Menlo Park, California
Posted
May 16, 2022
Required Education
Masters Degree/MBA
Position Type
Full time

Major Responsibilities and Duties:

  • Design and support molecular biology experiments to interrogate and identify new drug targets and preclinical development of existing targets in our pipeline
  • Hands-on work will include mammalian cell culture, drug/compound screening, and performing various molecular biology-based assays, including CRISPR-based cell line generation, flow cytometry, Western blotting, qRT-PCR, Immunofluorescence, and ELISA.
  • Perform experiments using various in vitro and ex vivo model systems/assays to elucidate molecular and phenotypic effects of target modulation
  • Drive new target discovery efforts by performing and managing genetic (for ex. CRISPR) screens both in-house and with CROs
  • Analyze and present experimental findings to the department and project teams.
  • Work collaboratively on multiple projects concurrently and contribute to activities across functions.

 

Qualifications:

1)     PhD or Master’s degree in Biological Sciences/Pharmacology in an oncology-related field. Strong preference for candidates with background in Cell cycle and DNA damage research.

2)     At least 0-2 years (PhD) or 8-10 years (M.Sc) of hands-on in vitro experience in cancer biology,

3)     Thorough experience in cancer cell/tissue culture and high-throughput assay development are required.

4)     Hands-on experience with various in vitro laboratory techniques is required, including Western blotting, qRT-PCR, immunofluorescence, RNAi, CRISPR, and flow cytometry. Strong preference for candidates with CRISPR screening experience

5)     Capable of working independently in a fast-paced, team-oriented environment, demonstrating solid and focused organizational skills

6)     Confidence in troubleshooting assays, performing and learning new data acquisition and analysis skills are required.

7)     Great communication skills and team spirit is a must; ability to communicate results with colleagues and with the biology team at meetings is required.