Associate Scientist, Upstream Pd

Austin, TX
May 15, 2022
Lone Star Bio
Required Education
Associate Degree
Position Type
Full time
div>Job DetailsLevel EntryJob Location TX-9301 - Austin, TXPosition Type Full TimeEducation Level 4 Year DegreeTravel Percentage NoneJob Shift DayJob Category Biopharmaceutical Development

Company Overview:


Molecular Templates is a clinical-stage biopharmaceutical company focused on the discovery and development of differentiated, targeted, biologic therapeutics.  Our proprietary biologic drug platform technology, known as engineered toxin bodies, or ETBs, leverages the resident biology of a genetically engineered form of Shiga-like Toxin A subunit to create novel therapies with potent and differentiated mechanisms of action for cancer and other serious diseases.  MTEM currently has multiple clinical-stage ETB candidates in development including MT-5111, MT-0169, and MT-6402.  Additional preclinical compounds derived from our ETB platform technology are being advanced toward clinical development. Additional information about Molecular Templates can be obtained at   


Position Overview:


Molecular Templates is seeking an experienced and highly motivated professional to support upstream processing for production activities. This position will perform functions related to production and GMP manufacturing operations, including routine protein expression using microbial fermentation, equipment set-up and calibration, and media preparation. This position will also be responsible for general facility and equipment preventative maintenance and sanitization. This will require excellent technical skills and strict adherence to Standard Operating Procedure (SOP) guidelines and verbal instructions and accurate and timely completion of manufacturing batch records.


Job Responsibilities will include:


  • Perform protein expression by microbial fermentation. This includes but not limited to: cell culture, cell banking, bioreactor operation, cell plating, cell harvesting, media preparation, equipment cleaning and sterilization, process data recording.
  • Conduct limited characterization of metabolic products and protein expression using common laboratory techniques.
  • Complete required documentation in an accurate and timely manner, strictly adhering to established SOPs and regulatory requirements.
  • Adhere to production schedules and timelines
  • Ensure highest degree of personal safety and facility security throughout operations
  • Conduct general laboratory and equipment maintenance duties, including washing glassware, ordering raw materials, products and other resources, and maintaining inventory (e.g. buffer), conducting preventative and safety checks on facility and equipment
  • Assist with non-complex projects, such as facility sanitization and organization, implementation of new instrumentation or proposal of technical improvements, as needed




  • Associates’ degree in biology, biochemistry, microbiology, or chemical engineering or a closely-related field, plus a minimum of two (2) years relevant experience in GMP manufacturing environment or laboratory conducting or supporting protein expression methods using microbial fermentation, or a Bachelor’s degree in biology, biochemistry, microbiology, or chemical engineering or a closely-related field
  • Experience in biopharmaceutical industry, preferred
  • Excellent written and verbal communication skills
  • Proficient computer skills with knowledge of spreadsheet and word processing
  • Excellent problem-solving and analytical skills
  • Excellent organizational, time management and multi-tasking skills
  • Ability to meet deadlines and maintain production schedule
  • Ability to follow written and verbal instruction and work under supervision
  • Ability to understand and exercise basic mathematical calculations
  • Ability to work in a fast-paced, high-growth team environment
  • Ability to lift 75 lbs. manually or with additional assistance from staff and/or mechanical lifting equipment (e.g. dolly, cart, lift, hand truck, etc.). Must be able to stand, crouch, sit, bend, or stretch for extended periods of time.
  • Must possess flexibility to work varying schedules to support operations, such as occasional 12-hour shift or night shift


Reporting Structure:


This position has no supervisory responsibilities. This position reports to Senior Scientist, Upstream Process Development.



Molecular Templates celebrates and supports our differences and is proud to be an Equal Employment Opportunity employer.  We do not discriminate based upon race, religion, color, national origin, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, veteran status, disability, or any other legally protected characteristic.    

MTEM is committed to providing reasonable accommodations for qualified individuals.  If you need assistance with your application due to a disability, you may contact us at:  

By submitting a resume for consideration, applicants verify that they have read MTEM’s Applicant Privacy notice.