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Scientist 2, Plant Health Analytical Development

Employer
GreenLight Biosciences, Inc.
Location
Medford, MA
Start date
May 15, 2022

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ABOUT GREENLIGHT

At GreenLight we are working to solve two of the world's greatest problems: global food insecurity and equal access to vaccines and the associated health benefits. Unlike most corporations who can be required to put profits ahead of other principles, GreenLight is one of the first Public Benefit Corporations to be publicly traded and have a charter that requires a focus on how it benefits its employees, community and society and has a broad portfolio addressing key issues in plant health and human health (Nasdaq: GRNA) by leveraging the full potential of dsRNA and mRNA. The GreenLight team is over 300 people across our headquarters in Medford, MA, an R&D facility in Woburn, MA and an R&D facility in Research Triangle Park, NC. GreenLight also has a biomanufacturing plant in Rochester, NY. Initiatives include finding ways to support biodiversity, protect bees and other pollinators, treat rare diseases as well as develop vaccines.

At GreenLight, we believe inclusion is the way forward. We celebrate the power of working together to address humanity’s challenges, meet the needs of underserved populations, and push the boundaries of scientific discovery. Fueled by our aspiration for a true sense of belonging, our talented teams embody the principles of diversity and equality as we strive to bring food security, medicine, and healthcare to everyone—paving the way for a sustainable future. For more information, visit www.greenlightbio.com.

POSITION

Greenlight Biosciences is developing cutting edge RNA technologies that address global challenges in food security, pollinator safety, and human health. GreenLight is seeking a highly motivated and collaborative Scientist to join our Plant Health Analytical Development team supporting RNAi product development. In this role you will work alongside a team of Scientists and Research Associates at our Medford, MA location who support our product, regulatory, and commercial development efforts across the Plant Health program. The team develops and performs assays required for regulatory studies (e.g. ecotoxicology, environmental fate, product chemistry, enforcement methods) and product characterization. The ideal candidate will have in-depth experience developing and executing methods that characterize plant health products, preferably biomolecules such as RNAi, proteins, or other bioactives. Strong interpersonal skills and the ability to thrive in a cross-functional team working to deliver against aggressive deadlines is essential. Experience with techniques necessary to advance agricultural products towards EPA approval is strongly preferred. Strong technical, organizational, and communication skills, and the ability and drive to maintain commitment to scientific excellence and high-quality work in a fast-paced, milestone-driven company are must-haves.

MAJOR RESPONSIBILITIES

  • Develop & execute HPLC and CE analytical methods for the quantification and characterization of our dsRNA active ingredient, formulation components, and related impurities
  • Develop, qualify, tech transfer, and monitor performance of enforcement methods at GreenLight’s various R&D and manufacturing sites, and at third party CROs
  • Develop methods using orthogonal techniques to confirm the identity of Greenlight’s dsRNA products
  • Develop procedures for sample extraction and handling to increase robustness of HPLC methods and allow higher throughput quantification, utilizing automated liquid handling where appropriate
  • Evaluate various technologies to characterize dsRNA active ingredient and assess stability in evolving formulation concepts
  • Provide supervision and mentorship to one or more Scientists / Research Associates on the team
  • Apply DOE methodology to optimize assays for minimal CV and increased reproducibility
  • Analyze, summarize, and present technical data to manager and other team members
  • Stay up to date with scientific and technical development within the field of analytical chemistry

PROFESSIONAL EXPERIENCE / QUALIFICATIONS

  • Ph.D. or M.S. in analytical chemistry, chemistry, biochemistry, or related field
  • 4+ years’ experience, including at least 2+ years’ in an analytical group at an industrial biotechnology company
  • Strong technical background in chemistry, with knowledge of nucleic acid chemistry, biochemistry, and microbial metabolism a plus
  • HPLC experience required, including optimization of mobile phase, gradients, and detection parameters
  • Proven track record of successful method development, including development of sample extraction methods and robust, specific LC quantification assays with acceptable performance criteria is required
  • Experience with biophysical/physical chemistry techniques is preferred (densitometry, DSC, DLS, etc.)
  • Experience with nucleotide and oligonucleotide / nucleic acid separations is preferred
  • Hands on experience troubleshooting analytical instrumentation is a plus
  • Must be highly motivated with high quality standards for one’s own work, strong communication skills, and an absolute commitment to team success

Greenlight Biosciences Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.

GreenLight requires proof of COVID-19 vaccination for its employees.

 

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