Principal Engineer

Cambridge, MA
May 15, 2022
Required Education
High School or equivalent
Position Type
Full time


If you feel like youre part of something bigger, its because you are. At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies. We are global collaborators who achieve togetherresearching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. Its time for a career you can be proud of.

Principal Engineer


What you will do

Lets do this. Lets change the world. In this vital role you will work with the Director of Process Development. This role will be based in Amgens Cambridge, Massachusetts location. The successful candidate will lead Amgens synthetics/oral dosage technical support. The scope of the role is to direct a team of 3-5 subject matter experts (SMEs) supporting the technology transfer and production of Amgens synthetic oral dosage forms. The team supports new product introductions, lifecycle changes and ongoing commercial production and development. Up to 30% US or international travel may be required to support Amgens drug product network.

As part of the team that also supports Amgens external parenteral biologics contract manufacturing network, this role also provides the opportunity for an individual to broaden their knowledge beyond oral dosage forms.

Provide technical and management leadership to a cross functional team of engineers and scientists.

Act as a drug product technical expert, to provide leadership and solutions when troubleshooting synthetic drug product manufacturing, for all processing stages such as blending, sieving, roller compaction, encapsulation, compression, coating etc.

Act as the accountable point of contact from the process development organization for product/process support for technology transfers and ongoing clinical and commercial drug product manufacturing at assigned contract manufacturing sites.

Build excellent business relationships with contract manufacturing partners, Global Operations, Contract Manufacturing Quality, and drug product process teams.

Lead functional and cross functional teams by setting the agenda, identifying issues and driving to goal completions and target dates.

Troubleshoot issues with drug product processing technologies and equipment.

Escalate issues, recommendations, and/or unresolved decisions in a professional and timely manner to the appropriate governance.

Holds others responsible or answerable for their actions, for exemplary job performance, and achieving business results.

Visit manufacturing sites to support key production milestones and build relationships


What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dedicated professional we seek is a collaborative partner with these qualifications.

Basic Qualifications:
  • Doctorate degree and 2 years of Engineering or Operations experience Or
  • Masters degree and 6 years of Engineering or Operations experience Or
  • Bachelors degree and 8 years of Engineering or Operations experience Or
  • Associates degree and 10 years of Engineering or Operations experience Or
  • High school diploma / GED and 12 years of Engineering or Operations experience
Preferred Qualifications:
  • Leading a team of 3-5 Senior/Principal Engineers and Scientists
  • Responsible for technical oversight of external synthetic drug product manufacturing
  • Providing commercial process development (MSAT) support to existing commercial and pipeline/launch products
  • Handling a diverse range of synthetic manufacturing technologies

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates professional and personal growth and well-being.

  • Vast opportunities to learn and move up and across our global organization
  • Diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act
  • Generous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefits
Apply now

for a career that defies imagination

In our quest to serve patients above all else, Amgen is the first to imagine, and the last to doubt. Join us.
Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Amgen requires all staff in the United States, Puerto Rico and Canada to be vaccinated from COVID 19 as a condition of employment. In accordance with applicable law, Amgen will provide reasonable accommodations to staff members who qualify on the basis of a medical reason or a sincerely held religious belief, practice, or observance. Such accommodation may not pose an undue hardship to Amgen, its operations, or its staff.