Senior Associate Scientist, In Vivo Pharmacology (Non-PhD)
At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science.In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.
The Tumor Microenvironment Thematic Research Center (TME TRC) is focused on developing therapeutic targets at the intersection of stromal, tumor and immune biology that enhance responsiveness to checkpoint blockade and other targeted therapies and transform response and durability rates for cancer patients. Our team comprises of scientists across multiple disciplines who are responsible for the biology and translational science necessary to support drug development from target identification through to first in human studies.
The In Vivo Pharmacology (IVP) Group within the TME TRC is dedicated to developing the IVP strategy and designing and executing on the IVP studies required to progress all the TME TRC preclinical drug development programs (both small and large molecule) from validation through to candidate selection and beyond.
In this role you will provide technical expertise in in vivo study planning and execution, participate in data interpretation and presentation. You will effectively collaborate with colleagues in IVP and with colleagues in cross-functional groups at TME TRC (discovery and translational research) and other supportive line functions (biotherapeutics, predictive science, and small molecule drug development)
Summary of Role:
You will execute in vivo studies, analyze, and present data. You will gain and provide technical and scientific in vivo pharmacology expertise to advance drug discovery programs from target identification/validationto IND enabling activities. You will interact and collaborate effectively in a multi-functional dynamic team environment.
Setup and executein vivostudies to validate targets, test novel drugs (small and large molecules), and combination strategies with a focus on oncology/immuno-oncology models (including syngeneic tumor models, xenograft models, models using transgenic lines, GEMMs etc) .
Generate graphs, statistics, and figures for in vivo data
Document data generated as a report in electronic notebook.
Present study findings within IVP and/or at cross-functional team meetings
Comply with IACUC and AALAC regulations.
Education and Experience:
Bachelor’s degree with 5+ years or Master’s degree with 2-5 years’ experience working with animals in academic or industry setting and/or translational drug discovery experience.
Hands on expertise in broadin vivopharmacology skills (dosing via different routes e.g. I.P, I.V, PO etc, tissue/blood collection).
Experience with syngeneic and xenograft tumor models is highly preferred.
Experience with data capturing and analysis software is preferred (i.e. electronic notebook, StudyLog, PRISM, Excel).
Experience in ex vivo assays like FACS is a plus.
Excellent interpersonal and communication skills to interact effectively with internal and external colleagues fostering a collaborative workplace environment.
Comfortable working in a fast-paced environment while supporting project timelines.
Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.
Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.
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